Description

Guanosine (CAS 118-00-3) is a purine nucleoside composed of guanine and ribose, with the molecular formula C₁₀H₁₃N₅O₅. This high-purity compound is essential in molecular biology, biochemistry, and pharmaceutical research, serving as a fundamental building block for RNA synthesis, nucleotide metabolism studies, and enzymatic assays. Guanosine is widely utilized in the production of antiviral and anticancer drugs due to its role in cellular signaling pathways, including GTP-mediated processes. Our product is rigorously tested for purity (>98% by HPLC) and is available in various forms to meet research and industrial standards. Suitable for cell culture applications, diagnostic reagents, and as a reference standard, this nucleoside is supplied with comprehensive analytical documentation, including NMR, MS, and HPLC data.

Properties

• CAS Number: 118-00-3
• Complexity: 446
• IUPAC Name: 2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-1H-purin-6-one
• InChI: InChI=1S/C10H13N5O5/c11-10-13-7-4(8(19)14-10)12-2-15(7)9-6(18)5(17)3(1-16)20-9/h2-3,5-6,9,16-18H,1H2,(H3,11,13,14,19)/t3-,5-,6-,9-/m1/s1
• InChI Key: NYHBQMYGNKIUIF-UUOKFMHZSA-N
• Exact Mass: 283.09166853
• Molecular Formula: C10H13N5O5
• Molecular Weight: 283.24
• SMILES: C1=NC2=C(N1[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O)N=C(NC2=O)N
• Topological: 155
• Monoisotopic Mass: 283.09166853
• Physical Description: Solid
• Synonyms: guanosine, 118-00-3, guanine riboside, vernine, Guanozin, Guanosin, Inosine, 2-amino-, 2-Amino-1,9-dihydro-9-beta-D-ribofuranosyl-6H-purin-6-one, USAF CB-11, Guanine-9-beta-D-ribofuranoside, 9-beta-D-Ribofuranosylguanine, beta-D-Ribofuranoside, guanine-9, Guanine, 9-beta-D-ribofuranosyl-, Ribofuranoside, guanine-9, beta-D-, 2(3H)-Imino-9-beta-D-ribofuranosyl-9H-purin-6(1H)-one, GUANINE-9:BETA-D-RIBOFURANOSIDE, Guo, AI3-52065, NSC 19994, 9-beta-D-ribofuranosyl-guanine, CHEBI:16750, EINECS 204-227-8, UNII-12133JR80S, 6H-Purin-6-one, 2-amino-1,9-dihydro-9-beta-D-ribofuranosyl-, 12133JR80S, DTXSID00893055, NSC-19994, 2-amino-9-beta-D-ribofuranosyl-1,9-dihydro-6H-purin-6-one, GUANOSINE (MART.), GUANOSINE [MART.], GUANOSINE (USP IMPURITY), GUANOSINE [USP IMPURITY], 85-30-3, ADENOSINE IMPURITY H (EP IMPURITY), ADENOSINE IMPURITY H [EP IMPURITY], 2-Amino-9-beta-D-ribofuranosyl-9H-purine-6(1H)-one, DTXCID601322998, 204-227-8, Vernine (VAN), MFCD00010182, Inosine, 2-amino- (VAN), DL-Guanosine, Guanine, 9-beta-D-ribofuranosyl- (VAN), 9-(beta-D-Ribofuranosyl)guanine, 2-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3H-purin-6(9H)-one, 2-AMINO-9-[(2R,3R,4S,5R)-3,4-DIHYDROXY-5-(HYDROXYMETHYL)OXOLAN-2-YL]-6,9-DIHYDRO-1H-PURIN-6-ONE, ST057098, 2-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one, 2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one, 2-Amino-9-beta-D-ribofuranosyl-1,9-dihydro-6H-purin-6-one (Guanosine), 9-[(4S,2R,3R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-aminohydropurin -6-one, 2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-1H-purin-6-one, 9-.beta.-D-ribofuranosylguanine, Ribonucleoside, Guanine, 9.beta.-d-ribofuranosyl-, .beta.-D-Ribofuranoside, guanine-9, 3h-guanosine, 2-amino-Inosine, 1odj, 2fqx, 9-B-D-RIBOFURANOSYLGUANINE, [3H]-guanosine, Inosine, 2-amino, 2-Amino-9-beta-D-ribofuranosyl-1,9-dihydro-6H-purin-6-one; Adenosine Imp. H (EP); Guanosine; Adenosine Impurity H, Guanosine, >=98%, GUANOSINE [MI], bmse000091, bmse001018, Epitope ID:141493, GUANOSINE [WHO-DD], 9-b-D-ribofuranosyl-Guanine, SCHEMBL21217, 2(3H)-Imino-9-.beta.-D-ribofuranosyl-9H-purin-6(1H)-one, b-D-Ribofuranoside guanine-9, 9-beta-D-ribofuranosyl guanine, CHEMBL375655, GTPL4567, SCHEMBL2774083, SCHEMBL3370382, SGCUT00093, Guanine-9-ss–D-ribofuranoside, SCHEMBL12212184, SCHEMBL27349775, 9-(ss–D-Ribofuranosyl)guanine, MSK6804, 9-beta-delta-ribofuranosyl-Guanine, Guanine-9-.beta.-D-ribofuranoside, beta-delta-Ribofuranoside guanine-9, Guanosine, >=97.0% (HPLC), HY-N0097, STR04471, to_000053, BBL033925, BDBM50366814, s2439, SBB003009, STK801927, AKOS005622500, AKOS007930368, AKOS015896931, AKOS032949764, CCG-267277, CS-W020018, DB02857, Ribofuranoside, guanine-9, .beta.-D-, NCGC00142496-01, NCGC00142496-02, BP-58656, DB-029875, G0171, NS00009027, Guanosine, Vetec(TM) reagent grade, >=98%, C00387, EN300-204342, Guanosine, suitable for cell culture, BioReagent, Q422462, Z1741979723, 2-Amino-1,9-dihydro-9-|A-D-ribofuranosyl-6H-purin-6-one, 2-Amino-1,9-dihydro-9-b-D-ribofuranosyl-6H-purin-6-one, 2-Amino-9-.beta.-D-ribofuranosyl-9-H-purine-6(1H)-one, 2-Amino-1,9-dihydro-9.beta.-d-ribofuranosyl-6H-purin-6-one, 2-AMINO-9-.BETA.-D-RIBOFURANOSYL-9H-PURINE-6(1H)-ONE, 6H-Purin-6-one, 2-amino-1,9-dihydro-9-beta-D-ribofuranosyl, 2-Amino-1,9-dihydro-9-beta-delta-ribofuranosyl-6H-purin-6-one, 6H-Purin-6-one, 2-amino-1,9-dihydro-9-.beta.-D-ribofuranosyl-, 2-AMINO-9-.BETA.-D-RIBOFURANOSYL-1,9-DIHYDRO-6H-PURIN-6-ONE, (2R,3R,4S,5R)-2-(2-amino-6-hydroxypurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol, 2-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxy-methyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one

Guanosine is extensively used in research as a precursor for mRNA synthesis and nucleotide metabolism studies. It plays a critical role in studying GTP-dependent signaling pathways and enzyme kinetics. Additionally, it serves as an impurity reference in pharmaceutical quality control (e.g., USP/EP standards). In cell culture, guanosine supports nucleotide supplementation for metabolic engineering applications.

Safety and Hazards

GHS Hazard Statements

• H301 (87.1%): Toxic if swallowed [Danger Acute toxicity, oral]

Precautionary Statements

• P264, P270, P301+P316, P321, P330, P405, and P501

Hazard Classes and Categories

• Acute Tox. 3 (87.1%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.