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Atomfair Flurothyl C4H4F6O CAS 333-36-8

Flurothyl (CAS 333-36-8) is a highly fluorinated organic compound with the molecular formula C4H4F6O and the IUPAC name 1,1,1-trifluoro-2-(2,2,2-trifluoroethoxy)ethane . This volatile liquid is characterized by its unique fluorinated ether structure, making it a valuable reagent in specialized chemical and pharmaceutical research. Flurothyl is known for its high purity and stability under controlled conditions, ensuring reliable performance in experimental applications. It is supplied in tightly sealed containers to maintain integrity and prevent degradation. Researchers and scientists utilize Flurothyl for its distinct reactivity profile, particularly in studies involving fluorinated compounds, CNS research, and anesthetic mechanisms.

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Description

Flurothyl (CAS 333-36-8) is a highly fluorinated organic compound with the molecular formula C4H4F6O and the IUPAC name 1,1,1-trifluoro-2-(2,2,2-trifluoroethoxy)ethane. This volatile liquid is characterized by its unique fluorinated ether structure, making it a valuable reagent in specialized chemical and pharmaceutical research. Flurothyl is known for its high purity and stability under controlled conditions, ensuring reliable performance in experimental applications. It is supplied in tightly sealed containers to maintain integrity and prevent degradation. Researchers and scientists utilize Flurothyl for its distinct reactivity profile, particularly in studies involving fluorinated compounds, CNS research, and anesthetic mechanisms.

Properties

  • CAS Number: 333-36-8
  • Complexity: 98.7
  • IUPAC Name: 1,1,1-trifluoro-2-(2,2,2-trifluoroethoxy)ethane
  • InChI: InChI=1S/C4H4F6O/c5-3(6,7)1-11-2-4(8,9)10/h1-2H2
  • InChI Key: KGPPDNUWZNWPSI-UHFFFAOYSA-N
  • Exact Mass: 182.01663372
  • Molecular Formula: C4H4F6O
  • Molecular Weight: 182.06
  • SMILES: C(C(F)(F)F)OCC(F)(F)F
  • Topological: 9.2
  • Monoisotopic Mass: 182.01663372
  • Melting Point: 122.5-123
  • Synonyms: Flurothyl, 333-36-8, Bis(2,2,2-trifluoroethyl) ether, Fluorothyl, Flurotyl, Indoklon, Bis(2,2,2-trifluoroethyl)ether, Bis(trifluoroethyl)ether, Flurotylum [INN-Latin], bis(trifluoroethyl) ether, Flurotilo [INN-Spanish], Flurotyl [INN], 2,2,2-Trifluoroethyl ether, Idoklon, Indiklon, Flurothyl [USAN:USP], SK&F 6539, Flurotyl (INN), Indoklon (TN), Flurothyl (USAN), NSC-760127, BRN 1811927, 9Z467FG2YK, DTXSID5046516, FLUROTHYL [MI], FLUROTHYL [USAN], HFE 356mff2, FLUROTYL [MART.], FLUROTYL [WHO-DD], (CF3CH2)2O, DTXCID3026516, di(2,2,2-Trifluoroethyl) ether, 4-01-00-01371 (Beilstein Handbook Reference), SK&F-6539, NSC 760127, Flurothyl (USAN:USP), Flurotylum (INN-Latin), Flurotilo (INN-Spanish), FLUROTYL (MART.), Ethane, 1,1′-oxybis(2,2,2-trifluoro)-, 626-793-9, kgppdnuwznwpsi-uhfffaoysa-n, Hexafluorodiethyl ether, 1,1,1-Trifluoro-2-(2,2,2-trifluoroethoxy)ethane, Flurotilo, SKF 6539, 2-(2,2,2-Trifluoroethoxy)-1,1,1-trifluoroethane, Ethane,1,1′-oxybis[2,2,2-trifluoro-, Ethane, 1,1′-oxybis(2,2,2-trifluoro-, ETHER, BIS(2,2,2-TRIFLUOROETHYL), NCGC00165991-01, Bis(2,2,2-trifluoroethyl) ether;Flurothyl, Flurotylum, Ethane, 1,1′-oxybis[2,2,2-trifluoro-, 2,2,2-trifluoro-1-(2,2,2-trifluoroethoxy)ethane, UNII-9Z467FG2YK, trifluoroethyl ether, HFE-356mff2, SCHEMBL120937, CHEMBL477874, SCHEMBL13858632, KGPPDNUWZNWPSI-UHFFFAOYSA-, CHEBI:134824, HMS2091M21, Pharmakon1600-01505430, HY-B1112, Tox21_112281, MFCD00010604, NSC760127, SBB089848, AKOS015913171, CCG-213435, CS-4711, DB08969, Bis(2,2,2-trifluoroethyl) ether, 99%, BS-43782, CAS-333-36-8, FB162433, SBI-0206927.P001, DB-048386, B1293, NS00068472, ST51041412, D04236, D88780, AB01563077_01, A821733, SR-05000001806, Q5462894, SR-05000001806-1, 1,1,1-Trifluoro-2-(2,2,2-trifluoroethoxy)ethane #, BRD-K14763542-001-02-3, 1,1,1-tris(fluoranyl)-2-[2,2,2-tris(fluoranyl)ethoxy]ethane, Bis(2,2,2-trifluoroethyl)ether, high puriy & water content 50 ppm max, InChI=1/C4H4F6O/c5-3(6,7)1-11-2-4(8,9)10/h1-2H2

Application

Flurothyl is primarily used in neuroscience research as a potent convulsant agent for studying seizure mechanisms and anticonvulsant drug efficacy. It has also been investigated for its anesthetic properties, though its clinical use is limited due to its strong convulsive effects. Additionally, Flurothyl serves as a fluorinated building block in organic synthesis, enabling the introduction of trifluoroethyl groups into target molecules. Its volatility and reactivity make it suitable for specialized laboratory applications under controlled conditions.

Safety and Hazards

GHS Hazard Statements

  • H225 (100%): Highly Flammable liquid and vapor [Danger Flammable liquids]
  • H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
  • H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
  • H335 (97.6%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

  • P210, P233, P240, P241, P242, P243, P261, P264, P264+P265, P271, P280, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P370+P378, P403+P233, P403+P235, P405, and P501

Hazard Classes and Categories

  • Flam. Liq. 2 (100%)
  • Skin Irrit. 2 (100%)
  • Eye Irrit. 2 (100%)
  • STOT SE 3 (97.6%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.

Disclaimer

Intended Use & Restrictions

This product is sold exclusively for laboratory research, analytical testing, or non-commercial purposes.

  • Strictly prohibited: Resale, repackaging, or formulation into commercial products.
  • Not approved for human/animal use, diagnostics, or manufacturing (including pharmaceuticals, agrochemicals, or consumer goods).

Patent & Regulatory Compliance

Certain molecules may be protected by active patents or regulatory restrictions.

  • Buyers must independently verify patent status (e.g., via USPTO/EPO/CNIPA) and comply with local laws.
  • Atomfair LLC does not provide legal assurances regarding patent non-infringement or jurisdictional compliance.

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  • Use this product only as permitted by law.
  • Indemnify Atomfair LLC against all claims arising from misuse, patent infringement, or regulatory violations.

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