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Atomfair Fabomotizole hydrochloride Afobazole HCl C15H22ClN3O2S CAS 173352-39-1

Fabomotizole Hydrochloride (CAS 173352-39-1) is a high-purity synthetic compound with the molecular formula C15H22ClN3O2S , widely utilized in pharmacological research and neurochemical studies. This hydrochloride salt of fabomotizole, also known as Afobazole HCl, exhibits selective anxiolytic properties by modulating sigma-1 receptors and influencing GABAergic systems without inducing sedation or muscle relaxation. Its IUPAC name, 4-[2-[(6-ethoxy-1H-benzimidazol-2-yl)sulfanyl]ethyl]morpholine;hydrochloride , reflects its unique benzimidazole-morpholine hybrid structure. Our product is rigorously tested via HPLC (>98% purity) and complies with ISO 9001 standards, ensuring optimal consistency for in vitro assays, animal studies, and drug development pipelines. Each batch is supplied in tamper-evident vials with comprehensive COA,…

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Description

Fabomotizole Hydrochloride (CAS 173352-39-1) is a high-purity synthetic compound with the molecular formula C15H22ClN3O2S, widely utilized in pharmacological research and neurochemical studies. This hydrochloride salt of fabomotizole, also known as Afobazole HCl, exhibits selective anxiolytic properties by modulating sigma-1 receptors and influencing GABAergic systems without inducing sedation or muscle relaxation. Its IUPAC name, 4-[2-[(6-ethoxy-1H-benzimidazol-2-yl)sulfanyl]ethyl]morpholine;hydrochloride, reflects its unique benzimidazole-morpholine hybrid structure. Our product is rigorously tested via HPLC (>98% purity) and complies with ISO 9001 standards, ensuring optimal consistency for in vitro assays, animal studies, and drug development pipelines. Each batch is supplied in tamper-evident vials with comprehensive COA, MSDS, and stability data.

Properties

  • CAS Number: 173352-39-1
  • Complexity: 315
  • IUPAC Name: 4-[2-[(6-ethoxy-1H-benzimidazol-2-yl)sulfanyl]ethyl]morpholine;hydrochloride
  • InChI: InChI=1S/C15H21N3O2S.ClH/c1-2-20-12-3-4-13-14(11-12)17-15(16-13)21-10-7-18-5-8-19-9-6-18;/h3-4,11H,2,5-10H2,1H3,(H,16,17);1H
  • InChI Key: MYSRFAUFQZYTOV-UHFFFAOYSA-N
  • Exact Mass: 343.1121258
  • Molecular Formula: C15H22ClN3O2S
  • Molecular Weight: 343.9
  • SMILES: CCOC1=CC2=C(C=C1)N=C(N2)SCCN3CCOCC3.Cl
  • Topological: 75.7
  • Monoisotopic Mass: 343.1121258
  • Synonyms: 173352-39-1, Afobazole hydrochloride, Fabomotizole hydrochloride, Fabomotizole (hydrochloride), Afobazol HCl, HDO6HX6NZU, 4-(2-((6-Ethoxy-1H-benzo[d]imidazol-2-yl)thio)ethyl)morpholine hydrochloride, SM-346, Afobazol hydrochloride, 4-[2-[(6-ethoxy-1H-benzimidazol-2-yl)sulfanyl]ethyl]morpholine;hydrochloride, Afobazole HCl, 4-(2-((5-ethoxy-1H-benzo[d]imidazol-2-yl)thio)ethyl)morpholine hydrochloride, CM346 hydrochloride, UNII-HDO6HX6NZU, Fabomotizole HCl, Afobazol HCl?, Afobazolehydrochloride, Fabomotizole?hydrochloride, OBENOXAZINE HYDROCHLORIDE, AFOBAZOL MONOHYDROCHLORIDE, AFOBAZOLE MONOHYDROCHLORIDE, DTXSID50938369, APHOBAZOLE MONOHYDROCHLORIDE, GLXC-05466, HMS5086L21, BCP29097, FABOMOTIZOLE MONOHYDROCHLORIDE, HY-14895A, SM 346, AKOS030526652, CS-3264, BS-15652, DA-73291, FABOMOTIZOLE HYDROCHLORIDE [MART.], FABOMOTIZOLE HYDROCHLORIDE [WHO-DD], S2474, FABOMOTIZOLE MONOHYDROCHLORIDE [MART.], D71044, 2-((2-Morpholino)ethylthio)-5-ethoxybenzimidazole, Q27279879, 2-[2-(morpholino)-ethylthio]-5-ethoxy-benzimidazole hydrochloride, 5-ethoxy-2-[2-(mor pholino)-ethylthio]benzimidazole hydrochloride, 1H-BENZIMIDAZOLE, 5-ETHOXY-2-((2-(4-MORPHOLINYL)ETHYL)THIO)-, MONOHYDROCHLORIDE, 1H-BENZIMIDAZOLE, 6-ETHOXY-2-((2-(4-MORPHOLINYL)ETHYL)THIO)-, HYDROCHLORIDE (1:1), 6-Ethoxy-2-{[2-(morpholin-4-yl)ethyl]sulfanyl}-1H-benzimidazole–hydrogen chloride (1/1)

Application

Fabomotizole hydrochloride is primarily investigated for its neuroprotective and anxiolytic effects in preclinical models, particularly in stress-induced disorders and cognitive impairment research. It demonstrates selective affinity for sigma-1 receptors, making it valuable for studying neurotransmitter modulation without benzodiazepine-like side effects. Researchers also explore its potential in mitigating oxidative stress and mitochondrial dysfunction in neurodegenerative diseases.

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Disclaimer

Intended Use & Restrictions

This product is sold exclusively for laboratory research, analytical testing, or non-commercial purposes.

  • Strictly prohibited: Resale, repackaging, or formulation into commercial products.
  • Not approved for human/animal use, diagnostics, or manufacturing (including pharmaceuticals, agrochemicals, or consumer goods).

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