Description
Ethyl Oxoacetate (CAS No. 924-44-7), also known as Ethyl Glyoxylate, is a highly versatile organic compound with the molecular formula C4H6O3. This clear to pale yellow liquid is widely utilized in synthetic organic chemistry as a key intermediate for the production of pharmaceuticals, agrochemicals, and specialty chemicals. Our high-purity Ethyl Oxoacetate is supplied as a 50% solution in toluene, ensuring stability and ease of handling. With its reactive aldehyde and ester functional groups, it serves as a crucial building block for heterocyclic synthesis, Strecker reactions, and multicomponent condensations. Suitable for research and industrial applications, this compound meets stringent quality standards and is packaged under inert conditions to maintain optimal purity and performance.
Properties
- CAS Number: 924-44-7
- Complexity: 77
- IUPAC Name: ethyl 2-oxoacetate
- InChI: InChI=1S/C4H6O3/c1-2-7-4(6)3-5/h3H,2H2,1H3
- InChI Key: DBPFRRFGLYGEJI-UHFFFAOYSA-N
- Exact Mass: 102.031694049
- Molecular Formula: C4H6O3
- Molecular Weight: 102.09
- SMILES: CCOC(=O)C=O
- Topological: 43.4
- Monoisotopic Mass: 102.031694049
- Synonyms: Ethyl glyoxylate, 924-44-7, Ethyl oxoacetate, ethyl 2-oxoacetate, Acetic acid, oxo-, ethyl ester, IXX9MQ1J1I, oxoacetic acid ethyl ester, Acetic acid, 2-oxo-, ethyl ester, Glyoxylic acid, ethyl ester, 2-oxoacetic acid, ethyl ester, EINECS 213-105-3, NSC 49206, NSC-49206, DTXSID6061282, CHEBI:53275, DTXCID7048794, 213-105-3, Ethyl glyoxalate, Glyoxylic acid ethyl ester, MFCD00044009, Ethyl Glyoxylate (>50per cent in Toluene), 192130-58-8, UNII-IXX9MQ1J1I, ethyloxoacetate, ethyl glyoxilate, ethyl oxo-acetate, ethyl-2-oxoacetate, glyoxalic acid ethylester, glyoxylic acid ethylester, Ethyl oxoacetate solution, Glyoxalic acid ethyl ester, oxo-acetic acid ethyl ester, SCHEMBL16187, oxo-acetic acid, ethyl ester, SCHEMBL733363, SCHEMBL3468596, SCHEMBL8435074, SCHEMBL10723340, NSC49206, STR04647, Ethyl 2-oxoacetate 50% in toluene, Ethyl glyoxalate – 50% in toluene, AKOS009158794, Ethyl 2-oxoacetate (50% in toluene), FE29894, Ethyl oxoacetate, 50% solution in toluene, DB-007537, NS00021386, D78103, Ethyl oxoacetate, tech, 50% solution in toluene, Ethyl glyoxalate, Tech grade, 30% solution in toluene, Q27124039, F0001-2228
Ethyl Oxoacetate is extensively used as a reagent in organic synthesis, particularly in the preparation of α-keto esters and heterocyclic compounds. It serves as a critical intermediate in pharmaceutical research for the development of active pharmaceutical ingredients (APIs). Additionally, its reactivity makes it valuable in agrochemical formulations and fine chemical manufacturing. The toluene-stabilized solution ensures safe handling and consistent results in laboratory and industrial settings.
Safety and Hazards
GHS Hazard Statements
- H225 (75%): Highly Flammable liquid and vapor [Danger Flammable liquids]
- H304 (50%): May be fatal if swallowed and enters airways [Danger Aspiration hazard]
- H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
- H317 (100%): May cause an allergic skin reaction [Warning Sensitization, Skin]
- H336 (50%): May cause drowsiness or dizziness [Warning Specific target organ toxicity, single exposure; Narcotic effects]
- H373 (50%): May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]
Precautionary Statements
- P210, P233, P240, P241, P242, P243, P260, P261, P264, P271, P272, P280, P301+P316, P302+P352, P303+P361+P353, P304+P340, P319, P321, P331, P332+P317, P333+P317, P362+P364, P370+P378, P403+P233, P403+P235, P405, and P501
Hazard Classes and Categories
- Flam. Liq. 2 (75%)
- Asp. Tox. 1 (50%)
- Skin Irrit. 2 (100%)
- Skin Sens. 1 (100%)
- STOT SE 3 (50%)
- STOT RE 2 (50%)
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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.


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