Description

Description

Ethyl Oxalyl Chloride (CAS 4755-77-5) is a highly reactive and versatile organic compound with the molecular formula C₄H₅ClO₃. Also known as Ethyl 2-chloro-2-oxoacetate, this clear to pale yellow liquid is widely used in organic synthesis, pharmaceutical manufacturing, and specialty chemical applications. Its IUPAC name is ethyl 2-chloro-2-oxoacetate, and it is characterized by its sharp, pungent odor and moisture-sensitive nature.

This compound is an essential reagent for introducing the oxalyl group into target molecules, making it valuable for the synthesis of esters, amides, and other derivatives. It is particularly useful in peptide coupling reactions, the production of agrochemicals, and as an intermediate in the synthesis of active pharmaceutical ingredients (APIs). Ethyl oxalyl chloride is typically stored under inert conditions to prevent hydrolysis and degradation.

Our high-purity grade (>98%) ensures optimal performance in sensitive reactions, with minimal impurities that could interfere with synthetic pathways. Proper handling requires the use of personal protective equipment (PPE) and adherence to standard safety protocols due to its corrosive and lachrymatory properties.

Application

Ethyl oxalyl chloride is primarily used as a key reagent in organic synthesis for the preparation of esters, amides, and other functionalized compounds. It serves as an effective acylating agent in peptide coupling reactions and the production of pharmaceutical intermediates. Additionally, it finds applications in agrochemical synthesis and the manufacture of specialty chemicals requiring the introduction of an oxalyl group.

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