Atomfair Ethyl 2-Fluoropropionate C5H9FO2 CAS 349-43-9

Description

Ethyl 2-Fluoropropionate (CAS: 349-43-9) is a high-purity fluorinated ester compound widely used in organic synthesis, pharmaceutical research, and specialty chemical applications. With the molecular formula C₅H₉FO₂, this reagent serves as a versatile building block for introducing fluorine-containing moieties into target molecules. Its clear liquid form and well-defined chemical properties make it ideal for precision reactions, including esterifications, nucleophilic substitutions, and fluorination processes. Packaged under inert conditions to ensure stability, our Ethyl 2-Fluoropropionate meets rigorous quality standards for researchers requiring consistent performance in sensitive synthetic workflows. Available in multiple quantities with detailed analytical documentation (GC/MS, NMR) to support your experimental needs.

Properties

• CAS Number: 349-43-9
• Complexity: 82.5
• IUPAC Name: ethyl 2-fluoropropanoate
• InChI: InChI=1S/C5H9FO2/c1-3-8-5(7)4(2)6/h4H,3H2,1-2H3
• InChI Key: ODMITNOQNBVSQG-UHFFFAOYSA-N
• Exact Mass: 120.05865769
• Molecular Formula: C5H9FO2
• Molecular Weight: 120.12
• SMILES: CCOC(=O)C(C)F
• Topological: 26.3
• Monoisotopic Mass: 120.05865769
• Synonyms: Ethyl 2-Fluoropropionate, 349-43-9, ethyl 2-fluoropropanoate, 127306-59-6, 2-Fluoropropionic Acid Ethyl Ester, Propanoic acid, 2-fluoro-, ethyl ester, Ethyl 2-Fluoro-propionate, 2-Fluoropropanoic Acid Ethyl Ester; 2-Fluoropropionic Acid Ethyl Ester; Ethyl 2-Fluoropropanoate; Ethyl alpha-Fluoropropionate; NSC 102760, MFCD01320801, NSC102760, Ethyl-2-fluoropropionate, SCHEMBL98593, SCHEMBL7662462, SCHEMBL10470528, BBL103911, STL557721, AKOS005063323, CS-W011209, FS-4018, NSC-102760, DB-001369, DB-001370, E0663, EN300-306523

Ethyl 2-Fluoropropionate is primarily employed as a fluorinated synthon in medicinal chemistry for modifying bioactive molecules. It acts as an intermediate in the production of agrochemicals and pharmaceuticals, particularly where fluorine substitution enhances metabolic stability. Researchers also utilize it in material science to synthesize specialty polymers with tailored surface properties. Its reactivity with Grignard reagents and organolithium compounds makes it valuable for constructing complex fluorinated architectures.

Safety and Hazards

GHS Hazard Statements

• H226 (100%): Flammable liquid and vapor [Warning Flammable liquids]
• H301 (33.3%): Toxic if swallowed [Danger Acute toxicity, oral]
• H311 (33.3%): Toxic in contact with skin [Danger Acute toxicity, dermal]
• H315 (33.3%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (66.7%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H331 (33.3%): Toxic if inhaled [Danger Acute toxicity, inhalation]

Precautionary Statements

• P210, P233, P240, P241, P242, P243, P261, P262, P264, P264+P265, P270, P271, P280, P301+P316, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P316, P321, P330, P332+P317, P337+P317, P361+P364, P362+P364, P370+P378, P403+P233, P403+P235, P405, and P501

Hazard Classes and Categories

• Flam. Liq. 3 (100%)
• Acute Tox. 3 (33.3%)
• Acute Tox. 3 (33.3%)
• Skin Irrit. 2 (33.3%)
• Eye Irrit. 2A (66.7%)
• Acute Tox. 3 (33.3%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.