Description

Ethyl 2-(3-chlorophenyl)acetate (CAS No. 14062-29-4) is a high-purity organic ester compound with the molecular formula C₁₀H₁₁ClO₂. This versatile chemical is widely utilized in pharmaceutical synthesis, agrochemical research, and specialty chemical manufacturing. The compound features a chlorophenyl moiety esterified with ethyl acetate, offering unique reactivity for nucleophilic substitution and coupling reactions. Our product is rigorously tested to ensure ≥98% purity (GC) and is supplied in sealed containers under inert atmosphere to guarantee stability. Available in quantities from grams to kilograms, it is ideal for medicinal chemistry, material science, and fragrance applications where precise molecular architecture is required.

Key specifications include: Molecular Weight: 198.65 g/mol, Boiling Point: ~265°C, Density: 1.15 g/cm³. The product is classified as an irritant (GHS07) and should be handled with appropriate personal protective equipment. Technical data sheets with detailed NMR, HPLC, and GC-MS characterization are available upon request.

Properties

• CAS Number: 14062-29-4
• Complexity: 170
• IUPAC Name: ethyl 2-(3-chlorophenyl)acetate
• InChI: InChI=1S/C10H11ClO2/c1-2-13-10(12)7-8-4-3-5-9(11)6-8/h3-6H,2,7H2,1H3
• InChI Key: SLNHJHHDMDGTGB-UHFFFAOYSA-N
• Exact Mass: 198.0447573
• Molecular Formula: C10H11ClO2
• Molecular Weight: 198.64
• SMILES: CCOC(=O)CC1=CC(=CC=C1)Cl
• Topological: 26.3
• Monoisotopic Mass: 198.0447573
• Synonyms: ethyl 2-(3-chlorophenyl)acetate, 14062-29-4, DTXSID60429056, DTXCID10379890, 816-544-4, Ethyl 3-chlorophenylacetate, Benzeneacetic acid, 3-chloro-, ethyl ester, ETHYL (3-CHLOROPHENYL)ACETATE, (3-Chloro-phenyl)-acetic acid ethyl ester, MFCD07787498, ethyl m-chlorophenylacetate, m-Chloro Phenylacetic Acid ethyl Ester, (3-CHLOROPHENYL)ACETIC ACID ETHYL ESTER, m-chlorophenylacetic acid ethyl ester, ethyl(3-chlorophenyl)acetate, SCHEMBL406058, CHEBI:194779, SLNHJHHDMDGTGB-UHFFFAOYSA-N, PAA06229, AKOS011681261, AS-37711, SY104530, DB-063342, CS-0151603, EN300-82888, Z982130886

Application

Ethyl 2-(3-chlorophenyl)acetate serves as a key intermediate in the synthesis of non-steroidal anti-inflammatory drugs (NSAIDs) and other pharmacologically active compounds. Researchers employ this ester in palladium-catalyzed cross-coupling reactions to construct complex biaryl systems. In material science, it functions as a precursor for liquid crystal monomers and specialty polymers. The compound’s chlorine substituent provides an orthogonal reactive site for further functionalization in multi-step synthetic routes.

Safety and Hazards

GHS Hazard Statements

• H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]

Precautionary Statements

• P264, P270, P301+P317, P330, and P501

Hazard Classes and Categories

• Acute Tox. 4 (100%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.