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Atomfair Ethoxyacetyl chloride C4H7ClO2 CAS 14077-58-8

Ethoxyacetyl Chloride (CAS 14077-58-8) is a highly reactive organic compound with the molecular formula C4H7ClO2. This clear to pale yellow liquid is an essential acyl chloride derivative, widely utilized in organic synthesis and pharmaceutical research. Its IUPAC name, 2-ethoxyacetyl chloride , reflects its ethoxy-substituted acetyl chloride structure, making it a valuable intermediate for introducing ethoxyacetyl groups into target molecules. With a purity of ≥95%, our Ethoxyacetyl Chloride is rigorously tested for quality and consistency, ensuring optimal performance in demanding applications. It is moisture-sensitive and should be stored under inert conditions to prevent hydrolysis. Suitable for use in nucleophilic substitution reactions,…

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Description

Ethoxyacetyl Chloride (CAS 14077-58-8) is a highly reactive organic compound with the molecular formula C4H7ClO2. This clear to pale yellow liquid is an essential acyl chloride derivative, widely utilized in organic synthesis and pharmaceutical research. Its IUPAC name, 2-ethoxyacetyl chloride, reflects its ethoxy-substituted acetyl chloride structure, making it a valuable intermediate for introducing ethoxyacetyl groups into target molecules.

With a purity of ≥95%, our Ethoxyacetyl Chloride is rigorously tested for quality and consistency, ensuring optimal performance in demanding applications. It is moisture-sensitive and should be stored under inert conditions to prevent hydrolysis. Suitable for use in nucleophilic substitution reactions, esterifications, and amide bond formations, this compound is a versatile tool for researchers in medicinal chemistry, agrochemical development, and material science.

Synonyms: 2-ethoxyacetyl chloride, EINECS 237-930-3, DTXSID50161473

Properties

  • CAS Number: 14077-58-8
  • Complexity: 62.7
  • IUPAC Name: 2-ethoxyacetyl chloride
  • InChI: InChI=1S/C4H7ClO2/c1-2-7-3-4(5)6/h2-3H2,1H3
  • InChI Key: ZPMWWAIBJJFPPQ-UHFFFAOYSA-N
  • Exact Mass: 122.0134572
  • Molecular Formula: C4H7ClO2
  • Molecular Weight: 122.55
  • SMILES: CCOCC(=O)Cl
  • Topological: 26.3
  • Monoisotopic Mass: 122.0134572
  • Synonyms: 2-ethoxyacetyl chloride, 14077-58-8, Ethoxyacetyl chloride, EINECS 237-930-3, DTXSID50161473, DTXCID5083964, 237-930-3, Acetyl chloride, 2-ethoxy-, Ethoxyacetylchloride, 2-Ethoxyacetylchloride, ethoxy-acetyl chloride, alpha-Ethoxyacetyl Chloride; Ethoxyacetic Acid Chloride;, MFCD11170566, Ethoxy acetyl chloride, ethoxyacetic acid chloride, (2-Ethoxy)-acetyl chloride, SCHEMBL316214, SCHEMBL27233236, AKOS009218031, BS-21408, DB-000281, NS00024565, E79167, EN300-781048, F2190-0030

Application

Ethoxyacetyl Chloride is primarily used as a key reagent in the synthesis of esters, amides, and other acylated derivatives. It serves as an intermediate in the production of pharmaceuticals, agrochemicals, and specialty chemicals. Researchers employ this compound for introducing the ethoxyacetyl moiety into complex molecules, enabling the development of novel bioactive compounds.

Safety and Hazards

GHS Hazard Statements

  • H226 (100%): Flammable liquid and vapor [Warning Flammable liquids]
  • H290 (16.7%): May be corrosive to metals [Warning Corrosive to Metals]
  • H314 (100%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]
  • H318 (16.7%): Causes serious eye damage [Danger Serious eye damage/eye irritation]
  • H332 (83.3%): Harmful if inhaled [Warning Acute toxicity, inhalation]

Precautionary Statements

  • P210, P233, P234, P240, P241, P242, P243, P260, P261, P264, P264+P265, P271, P280, P301+P330+P331, P302+P361+P354, P303+P361+P353, P304+P340, P305+P354+P338, P316, P317, P321, P363, P370+P378, P390, P403+P235, P405, P406, and P501

Hazard Classes and Categories

  • Flam. Liq. 3 (100%)
  • Met. Corr. 1 (16.7%)
  • Skin Corr. 1B (100%)
  • Eye Dam. 1 (16.7%)
  • Acute Tox. 4 (83.3%)

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.

Disclaimer

Intended Use & Restrictions

This product is sold exclusively for laboratory research, analytical testing, or non-commercial purposes.

  • Strictly prohibited: Resale, repackaging, or formulation into commercial products.
  • Not approved for human/animal use, diagnostics, or manufacturing (including pharmaceuticals, agrochemicals, or consumer goods).

Patent & Regulatory Compliance

Certain molecules may be protected by active patents or regulatory restrictions.

  • Buyers must independently verify patent status (e.g., via USPTO/EPO/CNIPA) and comply with local laws.
  • Atomfair LLC does not provide legal assurances regarding patent non-infringement or jurisdictional compliance.

Liability Release

By purchasing, the buyer agrees to:

  • Use this product only as permitted by law.
  • Indemnify Atomfair LLC against all claims arising from misuse, patent infringement, or regulatory violations.

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