Description

Ecamsule (CAS 92761-26-7), also known as Mexoryl SX, is a high-performance UV filter widely recognized for its exceptional photostability and broad-spectrum UVA protection. This synthetic organic compound, with the molecular formula C₂₈H₃₄O₈S₂, is specifically engineered to absorb ultraviolet radiation in the 290-400 nm range, making it a critical ingredient in advanced sun care formulations. Ecamsule is a terephthalylidene dicamphor sulfonic acid derivative, characterized by its unique molecular structure that ensures minimal degradation under prolonged sun exposure, thereby enhancing the longevity and efficacy of sunscreen products.

Developed by L’Oréal, Ecamsule is a patented ingredient approved by regulatory agencies worldwide, including the FDA (as Ecamsule [USAN]) and the EU. Its superior solubility in water and compatibility with other UV filters make it ideal for lightweight, non-greasy formulations such as daily moisturizers, serums, and high-SPF sunscreens. Ecamsule is particularly valued for its ability to prevent photoaging and oxidative stress caused by UVA rays, offering robust protection against long-term skin damage.

This product is supplied as a fine white powder or as a pre-dispersed solution for ease of formulation. It is rigorously tested for purity (>98%) and stability, ensuring compliance with international cosmetic standards (ISO, INCI, and ICH guidelines). Suitable for sensitive skin, Ecamsule is free from parabens, oxybenzone, and octinoxate, aligning with clean beauty trends.

Properties

• CAS Number: 92761-26-7
• Complexity: 1230
• IUPAC Name: [(3E)-3-[[4-[(E)-[7,7-dimethyl-3-oxo-4-(sulfomethyl)norbornan-2-ylidene]methyl]phenyl]methylene]-7,7-dimethyl-2-oxo-norbornan-1-yl]methanesulfonic acid
• InChI: InChI=1S/C28H34O8S2/c1-25(2)21-9-11-27(25,15-37(31,32)33)23(29)19(21)13-17-5-7-18(8-6-17)14-20-22-10-12-28(24(20)30,26(22,3)4)16-38(34,35)36/h5-8,13-14,21-22H,9-12,15-16H2,1-4H3,(H,31,32,33)(H,34,35,36)/b19-13+,20-14+
• InChI Key: HEAHZSUCFKFERC-IWGRKNQJSA-N
• Exact Mass: 562.16951039
• Molecular Formula: C28H34O8S2
• Molecular Weight: 562.7
• SMILES: CC1(C2(C(=O)/C(=C/C3=CC=C(C=C3)/C=C4/C(=O)C5(C(C4CC5)(C)C)CS(=O)(=O)O)/C1CC2)CS(=O)(=O)O)C
• Topological: 160
• Monoisotopic Mass: 562.16951039
• Color/Form: Solid
• Melting Point: 255 °C
• Stability/Shelf Life: Stable under recommended storage conditions.
• Dissociation Constants: pKa = 1.99 /sulfuric acid moiety/
• Synonyms: Ecamsule, Mexoryl, Mexoryl SX, Ecamsule [USAN], ECAMSULE [INN], ECAMSULE [MI], ECAMSULE [MART.], ECAMSULE [WHO-DD], ECAMSULE [ORANGE BOOK], Terephthalylidene dicamphor sulfonic acid, M94R1PM439, ANTHELIOS SX COMPONENT ECAMSULE, CAPITAL SOLEIL COMPONENT ECAMSULE, ECAMSULE (MART.), Ecamsul, Ecamsulum, 92761-26-7, NSC-760054, {3-[(4-{[7,7-dimethyl-3-oxo-4-(sulfomethyl)bicyclo[2.2.1]heptan-2-ylidene]methyl}phenyl)methylidene]-7,7-dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl}methanesulfonic acid, DTXSID80869056, (3-((4-((7,7-dimethyl-3-oxo-4-(sulfomethyl)bicyclo(2.2.1)heptan-2-ylidene)methyl)phenyl)methylidene)-7,7-dimethyl-2-oxobicyclo(2.2.1)heptan-1-yl)methanesulfonic acid, Terephthalylidene-3,3′-dicamphor-10,10′-disulfonic acid, DTXCID50817089, (+-)-(3E,3’E)-(p-Phenylenedimethylidyne)bis(2-oxo-10-bornanesulfonic acid), (+-)-(3E,3’E)-3,3′-(p-Phenylenedimethylidyne)bis(2-oxo-10-bornanesulfonic acid), ECAMSULE COMPONENT OF ANTHELIOS SX, ECAMSULE COMPONENT OF CAPITAL SOLEIL, TEREPHTHALYLIDENE DICAMPHOR SULFONIC ACID [INCI], ((3Z)-3-((4-((Z)-(7,7-dimethyl-3-oxo-4-(sulfomethyl)norbornan-2-ylidene)methyl)phenyl)methylidene)-7,7-dimethyl-2-oxo-norbornan-1-yl)methanesulfonic acid, 922-216-2, 90457-82-2, SCHEMBL9927140, HEAHZSUCFKFERC-IWGRKNQJSA-N, AKOS040759635, DB09534, AS-76600, EN300-33336721, (+/-)-(3E,3’E)-3,3′-(P-PHENYLENEDIMETHYLIDYNE)BIS(2-OXO-10-BORNANESULFONIC ACID)

Ecamsule is primarily used in sun care products to provide stable, broad-spectrum UVA protection. It is formulated into facial sunscreens, anti-aging creams, and daily wear SPF moisturizers due to its photostability and compatibility with other actives. Its water-soluble nature allows for lightweight, non-comedogenic textures ideal for sensitive or acne-prone skin. Ecamsule is also incorporated into hybrid sunscreens combining chemical and mineral filters for enhanced efficacy.

Safety and Hazards

GHS Hazard Statements

• H318: Causes serious eye damage [Danger Serious eye damage/eye irritation]

Precautionary Statements

• P264+P265, P280, P305+P354+P338, and P317

Hazard Classes and Categories

• Eye Dam. 1 (100%)

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.