Description

Drometrizole trisiloxane (CAS: 155633-54-8) is a highly effective organic UV absorber and light stabilizer, widely utilized in advanced photoprotective formulations. With the molecular formula C₂₄H₃₉N₃O₃Si₃ and IUPAC name 2-(benzotriazol-2-yl)-4-methyl-6-[2-methyl-3-[methyl-bis(trimethylsilyloxy)silyl]propyl]phenol, this compound exhibits exceptional broad-spectrum UV absorption, covering both UVA (320-400 nm) and UVB (280-320 nm) ranges. Its unique trisiloxane backbone enhances compatibility with silicone-based matrices, making it ideal for high-performance sunscreens, coatings, and polymer stabilization. Drometrizole trisiloxane is valued for its photostability, low volatility, and resistance to degradation under prolonged UV exposure. Available in high-purity grades (>98%), it meets stringent requirements for cosmetic, pharmaceutical, and industrial applications.

Properties

• CAS Number: 155633-54-8
• Complexity: 613
• IUPAC Name: 2-(benzotriazol-2-yl)-4-methyl-6-[2-methyl-3-[methyl-bis(trimethylsilyloxy)silyl]propyl]phenol
• InChI: InChI=1S/C24H39N3O3Si3/c1-18-14-20(15-19(2)17-33(9,29-31(3,4)5)30-32(6,7)8)24(28)23(16-18)27-25-21-12-10-11-13-22(21)26-27/h10-14,16,19,28H,15,17H2,1-9H3
• InChI Key: HUVYTMDMDZRHBN-UHFFFAOYSA-N
• Exact Mass: 501.22992172
• Molecular Formula: C24H39N3O3Si3
• Molecular Weight: 501.8
• SMILES: CC1=CC(=C(C(=C1)N2N=C3C=CC=CC3=N2)O)CC(C)C[Si](C)(O[Si](C)(C)C)O[Si](C)(C)C
• Topological: 69.4
• Monoisotopic Mass: 501.22992172
• Synonyms: Drometrizole trisiloxane, 155633-54-8, Silatrizole, Mexoryl XL, Drometrizole trisiloxane [WHO-DD], UNII-HC22845I1X, Drometrizole trisiloxane [INCI], OR 10154, OR-10154, Phenol, 2-(2H-benzotriazol-2-yl)-4-methyl-6-[2-methyl-3-[1,3,3,3-tetramethyl-1-[(trimethylsilyl)oxy]-1-disiloxanyl]propyl]-, HC22845I1X, DTXSID40431753, 2-(2H-1,2,3-benzotriazol-2-yl)-4-methyl-6-[2-methyl-3-(2,2,4,6,6-pentamethyl-3,5-dioxa-2,4,6-trisilaheptan-4-yl)propyl]phenol, Phenol, 2-(2H-benzotriazol-2-yl)-4-methyl-6-(2-methyl-3-(1,3,3,3-tetramethyl-1-((trimethylsilyl)oxy)-1-disiloxanyl)propyl)-, Phenol, 2-(2H-benzotriazol-2-yl)-4-methyl-6-(2-methyl-3-(1,3,3,3-tetramethyl-1-((trimethylsilyl)oxy)disiloxanyl)propyl)-, DROMETRIZOLE TRISILOXANE [USP-RS], DROMETRIZOLE TRISILOXANE (USP-RS), 2-(2H-1,2,3-benzotriazol-2-yl)-4-methyl-6-(2-methyl-3-(2,2,4,6,6-pentamethyl-3,5-dioxa-2,4,6-trisilaheptan-4-yl)propyl)phenol, DTXCID30382583, 422-940-4, 919-634-2, 2-(benzotriazol-2-yl)-4-methyl-6-[2-methyl-3-[methyl-bis(trimethylsilyloxy)silyl]propyl]phenol, 2-(2H-Benzo[d][1,2,3]triazol-2-yl)-6-(3-(1,1,1,3,5,5,5-heptamethyltrisiloxan-3-yl)-2-methylpropyl)-4-methylphenol, 2-(2H-Benzo[d][1,2,3]triazol-2-yl)-6-[3-(1,1,1,3,5,5,5-heptamethyltrisiloxan-3-yl)-2-methylpropyl]-4-methylphenol, Mexoryl XL;Silatrizole, SCHEMBL15380, BCP28866, MFCD22373626, AKOS030621544, DB11585, HY-W419643, NCGC00532508-01, 2-(2h-benzotriazol-2-yl)-4-methyl-6-[2-methyl-3-[1,3,3,3-tetramethyl-1-[(trimethylsilyl)oxy]disiloxanyl]propyl]phenol, SY284373, TS-10004, DB-091411, CS-0539357, Drometrizole trisiloxane, analytical standard, G76453, EN300-19999992, Q5308268, Drometrizole trisiloxane, United States Pharmacopeia (USP) Reference Standard, 2-(2h-benzotriazol-2-yl)-4-methyl-6-(2-methyl-3-(1,3,3,3-tetramethyl-1-(trimethylsilyloxy)-disiloxanyl)propyl)phenol, 320341-73-9

Application

Drometrizole trisiloxane is primarily employed as a photostabilizer in sunscreens and cosmetic formulations to provide long-lasting UV protection. It is also used in coatings and plastics to prevent UV-induced degradation, extending product lifespan. The compound’s silicone compatibility makes it suitable for waterproof or sweat-resistant personal care products. Researchers utilize it in studies on photodegradation mechanisms and advanced material stabilization.

Safety and Hazards

GHS Hazard Statements

• Not Classified
• Reported as not meeting GHS hazard criteria by 1 of 1 companies. For more detailed information, please visit ECHA C&L website.

Hazard Classes and Categories

• Not Classified

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.