Description

DL-Serine hydrazide hydrochloride (CAS No. 55819-71-1) is a high-purity biochemical reagent with the molecular formula C₃H₁₀ClN₃O₂. This compound, also known as 2-amino-3-hydroxypropanehydrazide hydrochloride, is a derivative of serine featuring a hydrazide functional group. It is widely utilized in peptide synthesis, pharmaceutical research, and as a building block for more complex organic molecules. The hydrochloride salt form enhances its stability and solubility, making it suitable for various experimental conditions. Each batch undergoes rigorous quality control to ensure ≥95% purity (HPLC), meeting the stringent requirements of research and industrial applications. Available in crystalline form, it is packaged under inert conditions to maintain integrity.

Properties

• CAS Number: 55819-71-1
• Complexity: 84.6
• IUPAC Name: 2-amino-3-hydroxy-propanehydrazide;hydrochloride
• InChI: InChI=1S/C3H9N3O2.ClH/c4-2(1-7)3(8)6-5;/h2,7H,1,4-5H2,(H,6,8);1H
• InChI Key: JNWGUZKRVDKZBI-UHFFFAOYSA-N
• Exact Mass: 155.0461543
• Molecular Formula: C3H10ClN3O2
• Molecular Weight: 155.58
• SMILES: C(C(C(=O)NN)N)O.Cl
• Topological: 101
• Monoisotopic Mass: 155.0461543
• Synonyms: DL-serine hydrazide Hydrochloride, 2-amino-3-hydroxypropanehydrazide hydrochloride, DL-Serinohydrazide monohydrochloride, N2RG2WDD8S, EINECS 259-839-8, EC 259-839-8, SERINE, HYDRAZIDE, MONOHYDROCHLORIDE, DL-SERINE, HYDRAZIDE, MONOHYDROCHLORIDE, SERINE, HYDRAZIDE, HYDROCHLORIDE (1:1), 259-839-8, 55819-71-1, DL-Serinohydrazide HCl, 25317-90-2, MFCD08704793, (DL)-Serine hydrazide HCl, 2-AMINO-3-HYDROXYPROPANEHYDRAZIDE HCL, 2-amino-3-hydroxypropanehydrazide;hydrochloride, (DL)-Serine hydrazide hydrochloride, DL-Serinohydrazide hydrochloride, (2RS)-2-Amino-3-hydroxypropanohydrazide Hydrochloride, C3H10ClN3O2, Serine, hydrazide, monohydrochloride (9CI); DL-Serine, hydrazide, monohydrochloride; DL-Serine hydrazide hydrochloride; Benserazide Hydrochloride Impurity A as Hydrochloride; Benserazide Impurity A as Hydrochloride, EINECS 246-829-3, DL-SERINEHYDRAZIDEHYDROCHLORIDE, DL-Serine Hydrazide HCl, UNII-N2RG2WDD8S, MLS006010900, SCHEMBL17376966, DTXSID60971222, JNWGUZKRVDKZBI-UHFFFAOYSA-N, AKOS015848281, AS-46925, SMR004701778, SY038029, CS-0149906, F10936, 2-Amino-3-hydroxypropanehydrazide xhydrochloride, EN300-7359381, 2-Amino-3-hydroxypropanehydrazonic acid–hydrogen chloride (1/1)

Application

DL-Serine hydrazide hydrochloride is primarily used in peptide coupling reactions as a hydrazide precursor. It serves as a key intermediate in the synthesis of serine-based peptidomimetics and protease inhibitors. Researchers also employ it in bioconjugation strategies for labeling biomolecules. Its hydroxyl and hydrazide groups enable selective modifications in drug discovery workflows.

Safety and Hazards

GHS Hazard Statements

• H252 (69.2%): Self-heating in large quantities; may catch fire [Warning Self-heating substances and mixtures]
• H302 (76.9%): Harmful if swallowed [Warning Acute toxicity, oral]
• H315 (23.1%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (84.6%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H335 (23.1%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P235, P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, P407, P410, P413, P420, and P501

Hazard Classes and Categories

• Self-heat. 2 (69.2%)
• Acute Tox. 4 (76.9%)
• Skin Irrit. 2 (23.1%)
• Eye Irrit. 2 (84.6%)
• STOT SE 3 (23.1%)

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.