Atomfair Dimethyl 1-(2,2-dimethoxyethyl)-3-methoxy-4-oxo-1,4-dihydropyridine-2,5-dicarboxylate Dolutegravir intermediate 5 C14H19NO8

Description Dimethyl 1-(2,2-dimethoxyethyl)-3-methoxy-4-oxo-1,4-dihydropyridine-2,5-dicarboxylate (CAS No. 1646862-02-3) is a high-purity pyridine derivative widely utilized in pharmaceutical research and organic synthesis. With the molecular formula C14H19NO8, this compound serves as a critical intermediate in the synthesis of complex molecules, including the antiretroviral drug Dolutegravir . Its unique structure, featuring multiple ester and ether functional groups, enables versatile reactivity in nucleophilic substitutions and condensation reactions. This product is rigorously tested for purity and stability, ensuring optimal performance in laboratory and industrial applications. Available in various quantities, it is ideal for researchers requiring precise and reliable building blocks for drug development and chemical studies.

Description

Dimethyl 1-(2,2-dimethoxyethyl)-3-methoxy-4-oxo-1,4-dihydropyridine-2,5-dicarboxylate (CAS No. 1646862-02-3) is a high-purity pyridine derivative widely utilized in pharmaceutical research and organic synthesis. With the molecular formula C₁₄H₁₉NO₈, this compound serves as a critical intermediate in the synthesis of complex molecules, including the antiretroviral drug Dolutegravir. Its unique structure, featuring multiple ester and ether functional groups, enables versatile reactivity in nucleophilic substitutions and condensation reactions. This product is rigorously tested for purity and stability, ensuring optimal performance in laboratory and industrial applications. Available in various quantities, it is ideal for researchers requiring precise and reliable building blocks for drug development and chemical studies.

CAS No: 1646862-02-3
Molecular Formula: C14H19NO8
Molecular Weight: 329.30
Exact Mass: 329.11106656
Monoisotopic Mass: 329.11106656
IUPAC Name: dimethyl 1-(2,2-dimethoxyethyl)-3-methoxy-4-oxopyridine-2,5-dicarboxylate
SMILES: COC1=C(N(C=C(C1=O)C(=O)OC)CC(OC)OC)C(=O)OC
Synonyms: 1646862-02-3, Dimethyl 1-(2,2-dimethoxyethyl)-3-methoxy-4-oxo-1,4-dihydropyridine-2,5-dicarboxylate, Dimethyl-1-(2,2-dimethoxyethyl)-3-methoxy-4-oxo-1,4-dihydropyridine-2,5-dicarboxylate, dimethyl 1-(2,2-dimethoxyethyl)-3-methoxy-4-oxopyridine-2,5-dicarboxylate, Dolutegravir intermediate 5

Application

This compound is primarily employed as a key intermediate in the synthesis of Dolutegravir, an integrase inhibitor used in HIV treatment. Its reactive pyridine core facilitates the construction of heterocyclic frameworks in medicinal chemistry. Researchers also utilize it in the development of novel enzyme inhibitors and receptor modulators. Its multifunctional design allows for further derivatization in organic synthesis workflows.

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