Description

Difluoromethanesulfonylbenzene (CAS: 1535-65-5) is a high-purity sulfone compound with the molecular formula C₇H₆F₂O₂S. This specialized chemical is widely used in organic synthesis, pharmaceutical research, and material science due to its unique difluoromethylsulfonyl functional group. With a purity of ≥97%, it is ideal for precise applications requiring consistent reactivity and stability. The compound is supplied as a fine crystalline powder, ensuring easy handling and solubility in common organic solvents. Its robust molecular structure makes it a valuable intermediate for constructing complex molecules, particularly in fluorinated compound synthesis. Store in a cool, dry place under inert conditions to maintain integrity.

Properties

• CAS Number: 1535-65-5
• Complexity: 224
• IUPAC Name: difluoromethylsulfonylbenzene
• InChI: InChI=1S/C7H6F2O2S/c8-7(9)12(10,11)6-4-2-1-3-5-6/h1-5,7H
• InChI Key: LRHDNAVPELLXDL-UHFFFAOYSA-N
• Exact Mass: 192.00565693
• Molecular Formula: C7H6F2O2S
• Molecular Weight: 192.19
• SMILES: C1=CC=C(C=C1)S(=O)(=O)C(F)F
• Topological: 42.5
• Monoisotopic Mass: 192.00565693
• Synonyms: difluoromethanesulfonylbenzene, 802-873-0, ((Difluoromethyl)sulfonyl)benzene, 1535-65-5, DIFLUOROMETHYL PHENYL SULFONE, [(difluoromethyl)sulfonyl]benzene, Difluoromethylsulfonylbenzene, MFCD01050170, (Difluoro-methanesulfonyl)-benzene, Benzene, [(difluoromethyl)sulfonyl]-, (Difluoromethyl)sulfonylbenzene, (Difluoromethylsulfonyl)benzene, SCHEMBL514631, SCHEMBL719362, SCHEMBL5865848, SCHEMBL9012684, DTXSID60473498, [(Difluoromethyl)sulfonyl]-benzene, AKOS005762898, Difluoromethyl phenyl sulfone, >=97%, CS-W007530, DS-4358, SY029164, D4764, EN300-155029, Z276573140

Difluoromethanesulfonylbenzene serves as a key intermediate in the synthesis of fluorinated pharmaceuticals and agrochemicals. Its reactive sulfonyl group facilitates nucleophilic substitution reactions, making it valuable in cross-coupling and functionalization processes. Researchers utilize it to introduce difluoromethyl motifs into target molecules, enhancing metabolic stability in drug design. It is also employed in materials science for developing specialty polymers with tailored properties.

Safety and Hazards

GHS Hazard Statements

• H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]

Precautionary Statements

• P264, P264+P265, P280, P302+P352, P305+P351+P338, P321, P332+P317, P337+P317, and P362+P364

Hazard Classes and Categories

• Skin Irrit. 2 (100%)
• Eye Irrit. 2A (100%)

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.