Description

Diethyl Sulfate (CAS No. 64-67-5) is a highly versatile and reactive organosulfur compound with the molecular formula C₄H₁₀O₄S. This colorless, oily liquid is widely utilized as an ethylating agent in organic synthesis and industrial applications. Its IUPAC name, diethyl sulfate, reflects its structure as the diethyl ester of sulfuric acid. With a high boiling point and moderate solubility in water, Diethyl Sulfate is an essential reagent for introducing ethyl groups into nucleophilic substrates such as alcohols, amines, and thiols. Suitable for use in pharmaceuticals, agrochemicals, and dye manufacturing, this compound is handled with care due to its toxic and potentially carcinogenic properties. Packaged under strict quality control, our Diethyl Sulfate meets the highest purity standards for research and industrial applications.

Properties

• CAS Number: 64-67-5
• Complexity: 130
• IUPAC Name: diethyl sulfate
• InChI: InChI=1S/C4H10O4S/c1-3-7-9(5,6)8-4-2/h3-4H2,1-2H3
• InChI Key: DENRZWYUOJLTMF-UHFFFAOYSA-N
• LogP: log Kow= 1.14
• Exact Mass: 154.02997997
• Molecular Formula: C4H10O4S
• Molecular Weight: 154.19
• SMILES: CCOS(=O)(=O)OCC
• Topological: 61
• Monoisotopic Mass: 154.02997997
• Physical Description: Diethyl sulfate appears as a clear colorless liquid with a peppermint odor. Burns, though may be difficult to ignite. Corrosive to metals and tissue. It is a potent alkylating agent. Flash point is 104 °C .
• Color/Form: Colorless, oily liquid … darkens with age
• Odor: Peppermint odor
• Boiling Point: 409 °F at 760 mmHg
• Melting Point: -12 °F
• Flash Point: 220 °F
• Solubility: Miscible in alcohol and ether.
• Density: 1.1803 at 68 °F – Denser than water; will sink
• Vapor Density: 5.31
• Vapor Pressure: 0.21 [mmHg]
• Autoignition Temperature: 817 °F
• Viscosity: 1.79 centipoises @ 20 °C
• Refractive Index: Index of Refraction = 1.40037 @ 20 °C/D
• Synonyms: Diethyl sulfate, Diethyl sulphate, Sulfuric acid, diethyl ester, DIETHYLSULFATE, Sulfuric acid diethyl ester, Diethyl Monosulfate, CCRIS 242, HSDB 1636, UNII-K0FO4VFA7I, EINECS 200-589-6, UN1594, DTXSID1024045, CHEBI:34699, AI3-15355, NSC-56380, Sulphuric acid diethyl ester, DIETHYL SULFATE [MI], DIETHYLSULFATE [HSDB], DIETHYL SULFATE [IARC], DTXCID604045, EC 200-589-6, NSC56380, UN 1594, DIETHYL SULFATE (IARC), Et2SO4, Sufuric Acid Diethyl Ester, Diethyl ester sulfuric acid, DTXCID2023729, 208-758-6, denrzwyuojltmf-uhfffaoysa-n, dtxsid4043729, einecs 208-758-6, ethyl sulfate [mi], inchi=1/c4h10o4s/c1-3-7-9(5,6)8-4-2/h3-4h2,1-2h, nocas_43729, sulfuric acid monoethyl ester, unii-p3lk0hf3b7, 64-67-5, Diaethylsulfat, Diethylester kyseliny sirove, NSC 56380, MFCD00009099, K0FO4VFA7I, ethyl ethoxysulfonate, Diethyl tetraoxosulfate, Diaethylsulfat [German], DES (VAN), CAS-64-67-5, Diethylester kyseliny sirove [Czech], diethylsulphate, diethyl-sulphate, Ethyl sulfate (Et2SO4); DES; Diethyl sulfate; Ethyl sulfate; NSC 56380, diethylsulfuric acid, EtOSO3Et, Diethyl sulfate, 98%, Ethyl sulfate (Et2SO4), SCHEMBL1769, WLN: 2OSWO2, BIDD:ER0594, CHEMBL163100, SCHEMBL11379927, BCP25766, Tox21_202402, Tox21_300169, SBB060663, STL268863, AKOS009157686, FD12133, Diethyl sulfate [UN1594] [Poison], NCGC00164138-01, NCGC00164138-02, NCGC00164138-03, NCGC00253940-01, NCGC00259951-01, D0525, NS00008605, ST51046800, Sulfuric acid, diethyl ester;Diethyl sulphate, Q421338, F0001-1737

Application

Diethyl Sulfate is primarily employed as an ethylating agent in the synthesis of ethyl derivatives of various organic compounds. It is extensively used in the pharmaceutical industry for the production of ethyl esters and ethers. In agrochemical manufacturing, it serves as a key intermediate for ethylating pesticides and herbicides. Additionally, Diethyl Sulfate finds applications in the dye industry for modifying dye structures to enhance solubility or color properties. Due to its reactivity, it is also utilized in laboratory-scale alkylation reactions under controlled conditions.

Safety and Hazards

GHS Hazard Statements

• Not Classified

Precautionary Statements

• P203, P260, P262, P264, P264+P265, P270, P273, P280, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P354+P338, P308+P316, P316, P317, P318, P321, P330, P361+P364, P363, P405, and P501

Hazard Classes and Categories

• Acute Tox. 4 (99.8%)
• Acute Tox. 3 (52.4%)
• Acute Tox. 4 (47.9%)
• Skin Corr. 1B (100%)
• Eye Dam. 1 (59.2%)
• Acute Tox. 3 (13.2%)
• Acute Tox. 4 (86.8%)
• Muta. 1B (99.8%)
• Carc. 1B (99.8%)
• Aquatic Chronic 3 (13%)

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.