Atomfair Dexrazoxane Hydrochloride Dexrazoxane HCl, Cardioxane, Totect C11H17ClN4O4

Description Dexrazoxane Hydrochloride (CAS No. 1263283-43-7) is a high-purity pharmaceutical compound with the molecular formula C11H17ClN4O4. It is the hydrochloride salt of dexrazoxane, a cyclic derivative of EDTA, and is recognized by its IUPAC name 4-[(2S)-2-(3,5-dioxopiperazin-1-yl)propyl]piperazine-2,6-dione;hydrochloride . This compound is supplied as a white to off-white crystalline powder, ensuring optimal stability and solubility for research applications. Dexrazoxane Hydrochloride is widely utilized in cardioprotective research and as a chemoprotectant in oncology studies. Its high purity (>98%) makes it ideal for in vitro and in vivo studies, particularly in mitigating anthracycline-induced cardiotoxicity. Store in a cool, dry environment (2-8??C) to maintain integrity.

Description

Dexrazoxane Hydrochloride (CAS No. 1263283-43-7) is a high-purity pharmaceutical compound with the molecular formula C₁₁H₁₇ClN₄O₄. It is the hydrochloride salt of dexrazoxane, a cyclic derivative of EDTA, and is recognized by its IUPAC name 4-[(2S)-2-(3,5-dioxopiperazin-1-yl)propyl]piperazine-2,6-dione;hydrochloride. This compound is supplied as a white to off-white crystalline powder, ensuring optimal stability and solubility for research applications. Dexrazoxane Hydrochloride is widely utilized in cardioprotective research and as a chemoprotectant in oncology studies. Its high purity (>98%) makes it ideal for in vitro and in vivo studies, particularly in mitigating anthracycline-induced cardiotoxicity. Store in a cool, dry environment (2-8??C) to maintain integrity.

CAS No: 1263283-43-7
Molecular Formula: C11H17ClN4O4
Molecular Weight: 304.73
Exact Mass: 304.0938327
Monoisotopic Mass: 304.0938327
IUPAC Name: 4-[(2S)-2-(3,5-dioxopiperazin-1-yl)propyl]piperazine-2,6-dione;hydrochloride
SMILES: C[C@@H](CN1CC(=O)NC(=O)C1)N2CC(=O)NC(=O)C2.Cl
Synonyms: Dexrazoxane hydrochloride, 149003-01-0, Dexrazoxane HCl, Cardioxane, Totect

Application

Dexrazoxane Hydrochloride is primarily used as a cardioprotective agent in research involving anthracycline-based chemotherapy. It functions by chelating free iron and preventing the formation of reactive oxygen species (ROS), thereby reducing oxidative stress on cardiomyocytes. This compound is also studied for its potential in preventing doxorubicin-induced cardiotoxicity. Additionally, it serves as a model compound in pharmacokinetic and pharmacodynamic research due to its well-characterized metabolism.

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