Description

Closantel Sodium (CAS No. 61438-64-0) is a high-purity veterinary anthelmintic agent with the molecular formula C₂₂H₁₃Cl₂I₂N₂NaO₂. This sodium salt derivative of closantel is widely recognized for its potent antiparasitic properties, particularly against liver flukes and other helminths in livestock. The compound features a unique halogenated aromatic structure, enhancing its bioavailability and efficacy. Suitable for research and pharmaceutical formulation, our Closantel Sodium is rigorously tested for purity (≥98% by HPLC) and stability, ensuring reliable performance in in vitro and in vivo studies. Packaged under inert conditions to prevent degradation.

Properties

• CAS Number: 61438-64-0
• Complexity: 659
• IUPAC Name: sodium;2-[[5-chloro-4-[(4-chlorophenyl)-cyano-methyl]-2-methyl-phenyl]carbamoyl]-4,6-diiodo-phenolate
• InChI: InChI=1S/C22H14Cl2I2N2O2.Na/c1-11-6-15(17(10-27)12-2-4-13(23)5-3-12)18(24)9-20(11)28-22(30)16-7-14(25)8-19(26)21(16)29;/h2-9,17,29H,1H3,(H,28,30);/q;+1/p-1
• InChI Key: LREGMDNUOGTSIK-UHFFFAOYSA-M
• Exact Mass: 683.83412
• Molecular Formula: C22H13Cl2I2N2NaO2
• Molecular Weight: 685.1
• SMILES: CC1=CC(=C(C=C1NC(=O)C2=C(C(=CC(=C2)I)I)[O-])Cl)C(C#N)C3=CC=C(C=C3)Cl.[Na+]
• Topological: 76
• Monoisotopic Mass: 683.83412
• Synonyms: Closantel sodium, 61438-64-0, UNII-0ZBS9YC04P, 0ZBS9YC04P, EINECS 262-794-7, R-34828, 5′-CHLORO-4′-(4-CHLORO-.ALPHA.-CYANOBENZYL)-3,5-DI-IODOSALICYL-O-TOLUIDIDE, BENZAMIDE, N-(5-CHLORO-4-((4-CHLOROPHENYL)CYANOMETHYL)-2-METHYLPHENYL)-2-HYDROXY-3,5-DIIODO-, MONOSODIUM SALT, Benzamide, N-[5-chloro-4-[(4-chlorophenyl)cyanomethyl]-2-methylphenyl]-2-hydroxy-3,5-diiodo-, monosodium salt, NSC335306, 5′-CHLORO-4′-(4-CHLORO-ALPHA-CYANOBENZYL)-3,5-DI-IODOSALICYL-O-TOLUIDIDE, 262-794-7, Closantel (sodium), 61438-64-0 (sodium), Closantel Sodium Salt, N-(5-Chloro-4-((4-chlorophenyl)(cyano)methyl)-2-methylphenyl)-2-hydroxy-3,5-diiodobenzamide, sodium salt, sodium 2-((5-chloro-4-((4-chlorophenyl)(cyano)methyl)-2-methylphenyl)carbamoyl)-4,6-diiodophenolate, Benzamide, N-[5-chloro-4-[(4-chlorophenyl)cyanomethyl]-2-methylphenyl]-2-hydroxy-3,5-diiodo-, sodium salt (1:1); Benzamide, N-[5-chloro-4-[(4-chlorophenyl)cyanomethyl]-2-methylphenyl]-2-hydroxy-3,5-diiodo-, monosodium salt (9CI), MFCD03427328, sodium;2-[[5-chloro-4-[(4-chlorophenyl)-cyanomethyl]-2-methylphenyl]carbamoyl]-4,6-diiodophenolate, MSK8209Na, Closantel (sodium) (Standard), LREGMDNUOGTSIK-UHFFFAOYSA-M, HMS3652M14, HMS5082I14, HY-17596AR, HY-17596A, AKOS015894903, AKOS015994723, CCG-270373, CS-3976, KS-1256, Sodium N-(5-chloro-4-((4-chlorophenyl)cyanomethyl)-o-tolyl)-2-hydroxy-3,5-diiodobenzamidate, SW219512-1, C75881, Q27251068

Closantel Sodium is primarily used in veterinary medicine to treat parasitic infections in ruminants, including fascioliasis and haemonchosis. It acts by uncoupling oxidative phosphorylation in parasites, leading to energy depletion and death. Researchers also employ it in pharmacokinetic studies due to its prolonged half-life and tissue retention. Not for human use.

Safety and Hazards

GHS Hazard Statements

• H301 (77.5%): Toxic if swallowed [Danger Acute toxicity, oral]
• H302 (22.5%): Harmful if swallowed [Warning Acute toxicity, oral]
• H400 (70%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]
• H410 (70%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]

Precautionary Statements

• P264, P270, P273, P301+P316, P301+P317, P321, P330, P391, P405, and P501

Hazard Classes and Categories

• Acute Tox. 3 (77.5%)
• Acute Tox. 4 (22.5%)
• Aquatic Acute 1 (70%)
• Aquatic Chronic 1 (70%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.