Description

Cholesteryl Oleate (CAS No. 303-43-5) is a high-purity cholesterol ester derived from oleic acid, widely utilized in biochemical and pharmaceutical research. This compound, with the molecular formula C₄₅H₇₈O₂, is a critical component in lipid metabolism studies, serving as a model for low-density lipoprotein (LDL) and high-density lipoprotein (HDL) research. Its >=98% HPLC purity (detection at 205 nm) ensures reliability for sensitive applications, including cell culture, lipidomics, and diagnostic reagent development. Packaged under inert conditions to prevent oxidation, our Cholesteryl Oleate is ideal for synthesizing liposomes, studying atherosclerosis mechanisms, and evaluating lipid storage disorders.

Key Features:

• High-purity grade (≥98%) with validated HPLC analysis
• Stable under recommended storage conditions (-20°C, desiccated)
• Compatible with organic solvents (e.g., chloroform, ethanol)
• Used in LC-MS/MS and GC-MS lipid profiling

Properties

• CAS Number: 303-43-5
• Complexity: 976
• IUPAC Name: [(3S,8S,9S,10R,13R,14S,17R)-17-[(1R)-1,5-dimethylhexyl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] (Z)-octadec-9-enoate
• InChI: InChI=1S/C45H78O2/c1-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-25-43(46)47-38-30-32-44(5)37(34-38)26-27-39-41-29-28-40(36(4)24-22-23-35(2)3)45(41,6)33-31-42(39)44/h14-15,26,35-36,38-42H,7-13,16-25,27-34H2,1-6H3/b15-14-/t36-,38+,39+,40-,41+,42+,44+,45-/m1/s1
• InChI Key: RJECHNNFRHZQKU-RMUVNZEASA-N
• Exact Mass: 650.60018173
• Molecular Formula: C45H78O2
• Molecular Weight: 651.1
• SMILES: CCCCCCCC/C=CCCCCCCCC(=O)O[C@H]1CC[C@@]2([C@H]3CC[C@]4([C@H]([C@@H]3CC=C2C1)CC[C@@H]4[C@H](C)CCCC(C)C)C)C
• Topological: 26.3
• Monoisotopic Mass: 650.60018173
• Physical Description: White waxy solid; Odorless;
• Synonyms: Cholesteryl oleate, Oleoylcholesterol, Cholesterol Oleate, Cholesteryl cis-9-octadecenoate, Cholesteroyl-oleate, Oleic acid cholesteryl ester, 18:1 Cholesteryl ester, Cholest-5-en-3-beta-yl oleate, Cholesterol, oleate, Cholesteryl oleic ester, UNII-3DPK9KFN2M, CE(18:1), 3DPK9KFN2M, Cholesteryl oleate-9,10-t2, Cholest-5-en-3-ol (3beta)-, 3-[(9Z)-9-octadecenoate], CHEBI:46898, Cholesterol 3beta-oleate, YOFCO LC-CO-D, EINECS 206-142-1, 3beta-Hydroxy-5-cholestene 3-oleate, NSC 18186, [(3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] (Z)-octadec-9-enoate, Cholesterol, oleate (8CI), cholest-5-en-3b-yl (9Z-octadecenoate), CE(18:1(9Z)), 5-Cholesten-3b-ol 3-oleate, Cholesteryl oleate-9,10-3H, Cholesteryl [9,10-3H]oleate, DTXSID901014621, CHOLESTEROL 3.BETA.-OLEATE, OLEIC ACID, CHOLESTERYL ESTER, NSC-18186, Cholest-5-en-3-ol (3beta)-, (9Z)-9-octadecenoate, Cholest-5-en-3-ol (3.beta.)-, (9Z)-9-octadecenoate, Cholest-5-en-3-ol (3.beta.)-, 9-octadecenoate, (Z)-, CHOLEST-5-EN-3-.BETA.-YL OLEATE, Cholest-5-en-3-yl (9Z)-9-octadecenoate, Cholesterol Ester(18:1), (3beta)-cholest-5-en-3-ol, (Z)-9-octadecenoate, (3beta)-cholest-5-en-3-yl (9Z)-octadec-9-enoate, Cholest-5-en-3-ol (3beta)-, 9-octadecenoate, (Z)-, Cholesteryl (9,10-3H)oleate, Cholest-5-en-3-ol (3beta)-, 3-((9Z)-9-octadecenoate), Cholesterol Ester(18:1/0:0), CHOLEST-5-EN-3-OL (3.BETA.)-, 3-((9Z)-9-OCTADECENOATE), 1-oleoyl-cholesterol, cholesteryl 1-oleoate, cholest-5-en-3b-yl, cholesteryl 1-oleoic acid, CE(18:1/0:0), 18:1(9Z) Cholesterol ester, Cholesteryl-beta-delta-glucoside, cholesterol 1-(9Z-octadecenoate, cholesterol 1-(9Z-octadecenoate), Cholest-5-en-3-ol (3.beta.)-, 3-[(9Z)-9-octadecenoate], Cholesterol Ester(18:1n9/0:0), Cholesterol Ester(18:1w9/0:0), Cholesteryl cis-9-octadecenoic acid, cholesterol 1-(9Z-octadecenoic acid, cholesteryl oleate, (E)-isomer, Cholesteroyloleate, cholesterol 1-(9Z-octadecenoic acid), CE(18:1n9/0:0), CE(18:1w9/0:0), ((3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-((2R)-6-methylheptan-2-yl)-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta(a)phenanthren-3-yl) (Z)-octadec-9-enoate, Cholesteryl oleic acid, Cholest-5-en-3-ol (3b)-(Z)-9-octadecenoate, Cholest5en3betayl oleate, Cholest-5-en-3-ol (3b)-(Z)-9-octadecenoic acid, 5Cholesten3betaol 3oleate, Cholesteryl cis9octadecenoate, Cholest-5-en-3-b-yl oleate, 3betaHydroxy5cholestene 3oleate, Cholest-5-en-3-I2-yl oleate, CHOLESTERYL OLEATE [INCI], Cholest-5-en-3-b-yl oleic acid, DTXCID601437167, Cholest-5-en-3-I2-yl oleic acid, Cholesteryl (9Z-octadecenoic acid), Cholest-5-en-3-beta-yl oleic acid, Cholest5en3ol (3beta), (9Z)9octadecenoate, Cholest-5-en-3-yl (9Z)-9-octadecenoic acid, (3b)-Cholest-5-en-3-ol, (Z)-9-octadecenoate, Cholest5en3ol (3beta), 3((9Z)9octadecenoate), (3b)-Cholest-5-en-3-ol, (Z)-9-octadecenoic acid, (3beta)-Cholest-5-en-3-ol, (Z)-9-octadecenoic acid, rjechnnfrhzqku-pfondfgasa-n, rjechnnfrhzqku-rmuvnzeasa-n, 303-43-5, cholesteryloleate, Oleic Acid Cholesterol Ester, 5-Cholesten-3beta-ol 3-oleate, (3beta)-cholest-5-en-3-yl (9E)-octadec-9-enoate, MFCD00003645, CE 18:1, 2OB, Cholest-5-en-3-ss-yl oleate; Chloesteryl cis-9-octadecanoate; Cholesteryl oleic ester; Oleoylcholesterol, SCHEMBL132003, cholesteryl (9Z-octadecenoate), CHEMBL1097567, Cholesterol, oleate (6CI,8CI), LMST01020003, Oleic acid, cholesteryl ester (6CI), AKOS025311525, FC61961, BP-29625, BS-42184, HY-113217, CS-0059332, NS00013460, Cholest-5-en-3-yl (9Z)-9-octadecenoate #, F82232, Q27104577, Cholesteryl oleate, >=98% (HPLC; detection at 205 nm), Cholesteryl oleate-13C18, 99 atom % 13C, 95% (CP), 9-octadecenoic acid, (3beta)-cholest-5-en-3-yl ester, (9Z)-, Cholest-5-en-3-ol (3beta)-, (9Z)-9-octadecenoate (9CI), (3beta,9beta,14beta,17alpha)-cholest-5-en-3-yl (9Z)-octadec-9-enoate, Cholest-5-en-3-ol (3beta)-, 9-octadecenoate-9,10-t2, (Z)- (9CI)

Cholesteryl Oleate is extensively employed as a standard in lipidomics to quantify esterified cholesterol in plasma and tissues. It facilitates research on foam cell formation in atherosclerosis by mimicking lipid accumulation in macrophages. Additionally, it serves as a substrate for cholesteryl ester hydrolase assays and is critical in developing lipid nanoparticle (LNP) drug delivery systems.

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.