Atomfair (Chlorodifluoromethyl)benzene C7H5ClF2

Description (Chlorodifluoromethyl)benzene (CAS No. 349-50-8) is a high-purity fluorinated organic compound with the molecular formula C7H5ClF2. This specialty chemical, also known by its IUPAC name [chloro(difluoro)methyl]benzene , features a chlorodifluoromethyl group attached to a benzene ring, offering unique reactivity for synthetic applications. With a molecular weight of 158.56 g/mol, it is a clear, colorless to pale yellow liquid under standard conditions. This reagent is meticulously synthesized and purified to meet the stringent requirements of pharmaceutical, agrochemical, and materials science research. It is particularly valuable as a building block for the introduction of difluoromethyl and chloro-difluoromethyl motifs in medicinal chemistry and…

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Description

Description

(Chlorodifluoromethyl)benzene (CAS No. 349-50-8) is a high-purity fluorinated organic compound with the molecular formula C7H5ClF2. This specialty chemical, also known by its IUPAC name [chloro(difluoro)methyl]benzene, features a chlorodifluoromethyl group attached to a benzene ring, offering unique reactivity for synthetic applications. With a molecular weight of 158.56 g/mol, it is a clear, colorless to pale yellow liquid under standard conditions. This reagent is meticulously synthesized and purified to meet the stringent requirements of pharmaceutical, agrochemical, and materials science research. It is particularly valuable as a building block for the introduction of difluoromethyl and chloro-difluoromethyl motifs in medicinal chemistry and advanced material design. Packaged under inert atmosphere to ensure stability, each batch is accompanied by comprehensive analytical data including GC/MS, NMR, and HPLC purity reports.

  • CAS No: 349-50-8
  • Molecular Formula: C7H5ClF2
  • Molecular Weight: 162.56
  • Exact Mass: 162.0047842
  • Monoisotopic Mass: 162.0047842
  • IUPAC Name: [chloro(difluoro)methyl]benzene
  • SMILES: C1=CC=C(C=C1)C(F)(F)Cl
  • Synonyms: (Chlorodifluoromethyl)benzene, 349-50-8, [chloro(difluoro)methyl]benzene, Benzene, (chlorodifluoromethyl)-, Toluene, alpha-chloro-alpha,alpha-difluoro-

Application

(Chlorodifluoromethyl)benzene serves as a versatile intermediate in organic synthesis, particularly for the preparation of difluoromethylated aromatic compounds. It is employed in pharmaceutical research for the development of bioactive molecules with enhanced metabolic stability. The compound also finds use in material science for modifying polymer properties through fluorinated aromatic incorporation. Its reactivity in nucleophilic substitutions and radical reactions makes it valuable for constructing complex fluorinated architectures.

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