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Atomfair Busulfan Myleran, Busulphan, Leucosulfan C6H14O6S2

Description Busulfan (CAS 55-98-1) is a bifunctional alkylating agent with the molecular formula C6H14O6S2and the IUPAC name 4-methylsulfonyloxybutyl methanesulfonate . This white crystalline solid is a highly potent chemotherapeutic agent primarily used in conditioning regimens prior to hematopoietic stem cell transplantation. Busulfan exhibits exceptional stability under standard storage conditions and is soluble in organic solvents such as acetone and ethanol, though poorly soluble in water. As a DNA alkylating agent, it crosslinks DNA strands, inhibiting replication and transcription processes. Our high-purity Busulfan is rigorously tested via HPLC (>98% purity) and meets stringent pharmacopeial standards for research and clinical applications. Available…

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Description

Description

Busulfan (CAS 55-98-1) is a bifunctional alkylating agent with the molecular formula C6H14O6S2 and the IUPAC name 4-methylsulfonyloxybutyl methanesulfonate. This white crystalline solid is a highly potent chemotherapeutic agent primarily used in conditioning regimens prior to hematopoietic stem cell transplantation. Busulfan exhibits exceptional stability under standard storage conditions and is soluble in organic solvents such as acetone and ethanol, though poorly soluble in water. As a DNA alkylating agent, it crosslinks DNA strands, inhibiting replication and transcription processes. Our high-purity Busulfan is rigorously tested via HPLC (>98% purity) and meets stringent pharmacopeial standards for research and clinical applications. Available in gram to kilogram quantities with comprehensive analytical documentation including NMR, MS, and COA.

  • CAS No: 55-98-1
  • Molecular Formula: C6H14O6S2
  • Molecular Weight: 246.3
  • Exact Mass: 246.02318051
  • Monoisotopic Mass: 246.02318051
  • IUPAC Name: 4-methylsulfonyloxybutyl methanesulfonate
  • SMILES: CS(=O)(=O)OCCCCOS(=O)(=O)C
  • Synonyms: busulfan, 55-98-1, Myleran, Busulphan, Leucosulfan

Application

Busulfan is widely utilized as a myeloablative conditioning agent prior to bone marrow or stem cell transplantation in hematologic malignancies. It demonstrates particular efficacy in chronic myeloid leukemia (CML) treatment protocols. Recent research explores its potential in gene therapy conditioning regimens due to its potent immunosuppressive properties. The compound is also investigated for combination therapies with novel targeted agents in refractory hematologic disorders.

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