Description

Bromo(difluoro)acetyl fluoride (CAS 38126-07-7) is a highly specialized fluorinated organic compound with the molecular formula C₂BrF₃O. This reactive intermediate is widely utilized in advanced synthetic chemistry applications, particularly in the preparation of fluorinated pharmaceuticals, agrochemicals, and specialty materials. Its IUPAC name, 2-bromo-2,2-difluoroacetyl fluoride, reflects its unique molecular structure featuring both bromine and fluorine substituents, which contribute to its high reactivity and utility in nucleophilic substitution reactions.

This compound is supplied as a high-purity liquid (typically >95% by GC) and must be handled under inert conditions due to its moisture sensitivity. It is commonly used as a building block for the introduction of difluoromethyl and related fluorinated groups into target molecules. Researchers value Bromo(diffluoro)acetyl fluoride for its ability to participate in radical reactions and as a precursor for various fluorinated synthons.

Our product is manufactured under strict quality control standards and is available for research and development purposes. Proper personal protective equipment (PPE) including gloves, face shield, and fume hood are required when handling this material.

Properties

• CAS Number: 38126-07-7
• Complexity: 90.9
• IUPAC Name: 2-bromo-2,2-difluoro-acetyl fluoride
• InChI: InChI=1S/C2BrF3O/c3-2(5,6)1(4)7
• InChI Key: REOFZGQDJKOKFI-UHFFFAOYSA-N
• Exact Mass: 175.90846
• Molecular Formula: C2BrF3O
• Molecular Weight: 176.92
• SMILES: C(=O)(C(F)(F)Br)F
• Topological: 17.1
• Monoisotopic Mass: 175.90846
• Synonyms: 38126-07-7, Bromo(difluoro)acetyl fluoride, DTXSID40378336, DTXCID40329363, BROMODIFLUOROACETYL FLUORIDE, 2-bromo-2,2-difluoroacetyl fluoride, Bromodifluoroacetylfluoride, MFCD00153689, SCHEMBL4858511, bromodifluoroacetic acid fluoride, REOFZGQDJKOKFI-UHFFFAOYSA-N, AKOS005064063, DB-022978

Application

Bromo(difluoro)acetyl fluoride serves as a key intermediate in organic synthesis, particularly for introducing difluoromethyl groups into pharmaceutical candidates. It finds application in the preparation of fluorinated analogs of bioactive molecules, enhancing their metabolic stability and lipophilicity. The compound is also used in materials science for creating specialty fluoropolymers with unique surface properties. Its reactivity makes it valuable for constructing complex fluorinated architectures in medicinal chemistry programs.

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.