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Atomfair Boc-beta-Hoarg(Tos)-OH C19H30N4O6S

Description Boc-beta-Hoarg(Tos)-OH (CAS No. 136271-81-3) is a high-purity, protected amino acid derivative widely utilized in peptide synthesis and pharmaceutical research. With the molecular formula C19H30N4O6S , this compound features a tert -butoxycarbonyl (Boc) protecting group and a tosyl (Tos) moiety, ensuring stability during complex synthetic procedures. Its IUPAC name, (3S)-6-[[amino-[(4-methylphenyl)sulfonylamino]methylidene]amino]-3-[(2-methylpropan-2-yl)oxycarbonylamino]hexanoic acid , highlights its precise structural configuration, making it ideal for controlled modifications in peptide chains. This product is rigorously tested for purity (typically ??95% by HPLC) and is supplied as a crystalline solid, ensuring reproducibility in research applications. Suitable for SPPS (Solid-Phase Peptide Synthesis) and solution-phase synthesis, it is…

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Description

Description

Boc-beta-Hoarg(Tos)-OH (CAS No. 136271-81-3) is a high-purity, protected amino acid derivative widely utilized in peptide synthesis and pharmaceutical research. With the molecular formula C19H30N4O6S, this compound features a tert-butoxycarbonyl (Boc) protecting group and a tosyl (Tos) moiety, ensuring stability during complex synthetic procedures. Its IUPAC name, (3S)-6-[[amino-[(4-methylphenyl)sulfonylamino]methylidene]amino]-3-[(2-methylpropan-2-yl)oxycarbonylamino]hexanoic acid, highlights its precise structural configuration, making it ideal for controlled modifications in peptide chains. This product is rigorously tested for purity (typically ??95% by HPLC) and is supplied as a crystalline solid, ensuring reproducibility in research applications. Suitable for SPPS (Solid-Phase Peptide Synthesis) and solution-phase synthesis, it is a critical building block for developing novel therapeutics and biochemical probes.

  • CAS No: 136271-81-3
  • Molecular Formula: C19H30N4O6S
  • Molecular Weight: 442.5
  • Exact Mass: 442.18860586
  • Monoisotopic Mass: 442.18860586
  • IUPAC Name: (3S)-6-[[amino-[(4-methylphenyl)sulfonylamino]methylidene]amino]-3-[(2-methylpropan-2-yl)oxycarbonylamino]hexanoic acid
  • SMILES: CC1=CC=C(C=C1)S(=O)(=O)NC(=NCCC[C@@H](CC(=O)O)NC(=O)OC(C)(C)C)N
  • Synonyms: 136271-81-3, Boc-beta-Hoarg(Tos)-OH, BOC-L-BETA-HOMOARGININE(TOS), Boc-|A-HoArg(Tos)-OH, N-Boc-N’-tosyl-L-beta-homoarginine

Application

Boc-beta-Hoarg(Tos)-OH is primarily employed in peptide chemistry as a key intermediate for introducing homoarginine analogs into peptide sequences. Its dual-protected design (Boc and Tos groups) allows selective deprotection, enabling precise chain elongation. Researchers use it to study enzyme-substrate interactions, receptor binding, and protease resistance in modified peptides. It also serves as a precursor for synthesizing peptidomimetics and constrained peptides with enhanced bioavailability.

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