Description

(-)-Benzyl (R)-glycidyl ether (CAS: 14618-80-5) is a high-purity chiral epoxide compound with the molecular formula C₁₀H₁₂O₂. This optically active glycidyl ether is widely utilized in asymmetric synthesis, pharmaceutical intermediates, and fine chemical applications. Its (R)-configuration ensures precise stereochemical control in reactions, making it invaluable for researchers developing enantiomerically pure compounds. The benzyl-protected glycidyl group offers excellent reactivity in ring-opening polymerizations and nucleophilic substitutions. Supplied as a clear to pale yellow liquid, our product undergoes rigorous QC testing including GC, HPLC, and chiral analysis to guarantee ≥98% chemical and enantiomeric purity. Proper storage under inert atmosphere at 2-8°C is recommended to maintain stability. Hazardous upon contact (skin/eye irritant) – always handle with appropriate PPE in well-ventilated areas.

Properties

• CAS Number: 14618-80-5
• Complexity: 130
• IUPAC Name: (2R)-2-(benzyloxymethyl)oxirane
• InChI: InChI=1S/C10H12O2/c1-2-4-9(5-3-1)6-11-7-10-8-12-10/h1-5,10H,6-8H2/t10-/m0/s1
• InChI Key: QNYBOILAKBSWFG-JTQLQIEISA-N
• Exact Mass: 164.083729621
• Molecular Formula: C10H12O2
• Molecular Weight: 164.20
• SMILES: C1[C@@H](O1)COCC2=CC=CC=C2
• Topological: 21.8
• Monoisotopic Mass: 164.083729621
• Synonyms: (-)-Benzyl (R)-glycidyl ether, Benzyl (-)-glycidyl ether, 604-513-6, 14618-80-5, (r)-benzyloxymethyl-oxirane, (R)-(-)-Benzyl glycidyl ether, (R)-2-((Benzyloxy)methyl)oxirane, Benzyl (R)-(-)-Glycidyl Ether, (R)-Benzyl glycidyl ether, (R)-O-Benzylglycidol, (R)-(-)-Glycidyl benzyl ether, (2R)-2-(phenylmethoxymethyl)oxirane, (R)-(-)-2-(Benzyloxymethyl)oxirane, (R)-benzylglycidyl ether, (2R)-2-[(benzyloxy)methyl]oxirane, MFCD00068409, (R)-2-(benzyloxymethyl)oxirane, (R)-(-)-1-Benzyloxy-2,3-epoxypropane, (R)-2-[(benzyloxy)methyl]oxirane, CCRIS 6385, Propane, 1-(benzyloxy)-2,3-epoxy-, (S)-, (R)-(-)-Benzyloxymethyloxirane, (S)-1-(Benzyloxy)-2,3-epoxypropane, BRN 3588399, Oxirane, [(phenylmethoxy)methyl]-, (2R)-, (2R)-2-(benzyloxymethyl)oxirane, Oxirane, ((phenylmethoxy)methyl)-, (R)-, Propane, 1-(benzyloxy)-2,3-epoxy-, (R)-, (R)- benzyl glycidyl ether, benzyl r-(-)-glycidyl ether, SCHEMBL715660, benzyl(R)-(+)-glycidyl ether, benzyl(R)-(-)-glycidyl ether, (-)-benzyl-(R)-glycidyl ether, BDBM36041, benzyl (R)-(+)-glycidyl ether, DTXSID10932782, (2R)-benzyl 2-epoxypropyl ether, CS-B1359, GEO-04308, AKOS015888105, (R)-1-(Benzyloxy)-2,3-epoxypropane, AC-7034, (R)-(-)-2-(Benzyloxymethyl)-oxirane, (R)-(-)-Glycidyl benzyl ether, 99%, NCGC00166044-01, ((2R)oxiran-2-yl)(phenylmethoxy)methane, AS-12082, DB-005537, B2238, NS00124727, ST50405570, EN300-74956, I10135, Z1171222157

This chiral building block is essential for synthesizing β-adrenergic receptor agonists and other bioactive molecules requiring (R)-configuration. The epoxide ring enables facile nucleophilic attack for creating C-O or C-N bonds in drug intermediates. In materials science, it serves as a monomer for producing stereoregular polymers with controlled tacticity. Researchers also employ it in kinetic resolutions and as a precursor for chiral ligands in asymmetric catalysis.

Safety and Hazards

GHS Hazard Statements

• H315 (95.8%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (95.8%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H335 (85.4%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Skin Irrit. 2 (95.8%)
• Eye Irrit. 2 (95.8%)
• STOT SE 3 (85.4%)

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.