Description

Description

Benzyl 4-(2-Hydroxyethyl)piperazine-1-carboxylate (CAS No. 14000-67-0) is a high-purity synthetic organic compound with the molecular formula C₁₄H₂₀N₂O₃. This piperazine derivative features a benzyl carboxylate group and a 2-hydroxyethyl substituent, making it a versatile intermediate in pharmaceutical and biochemical research. The compound is supplied as a white to off-white crystalline powder with ??95% purity (HPLC), ensuring consistency for sensitive applications. It is soluble in common organic solvents such as DMSO, methanol, and dichloromethane but exhibits limited solubility in water. Store at 2-8??C in a tightly sealed container under inert gas to maintain stability. Ideal for use in peptide coupling, heterocyclic synthesis, and as a building block for drug discovery.

Application

Benzyl 4-(2-Hydroxyethyl)piperazine-1-carboxylate serves as a key intermediate in the synthesis of pharmacologically active compounds, particularly in the development of CNS-targeting drugs and enzyme inhibitors. Its hydroxyl group enables further functionalization via esterification or etherification, while the piperazine core contributes to binding affinity in receptor ligands. Researchers utilize this compound in combinatorial chemistry libraries for lead optimization. It is also employed in the preparation of chelating agents and polymer modifiers due to its dual functionality.

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