Description

Description

Benzo[d][1,3]dioxole-5-carbonyl fluoride (CAS No. 2254447-02-2) is a high-purity fluorinated organic compound with the molecular formula C₈H₅FO₃. This specialized reagent features a benzodioxole core functionalized with a reactive carbonyl fluoride group, making it a valuable building block for synthetic organic chemistry and pharmaceutical research. The compound is characterized by its unique molecular structure, combining the aromatic stability of the benzodioxole system with the electrophilic reactivity of the acyl fluoride moiety. Available in >95% purity by HPLC, this chemical is supplied in rigorously controlled conditions to ensure optimal stability and performance. Ideal for use in nucleophilic acyl substitution reactions, cross-coupling chemistry, and as a precursor for more complex heterocyclic systems.

Application

Benzo[d][1,3]dioxole-5-carbonyl fluoride serves as a key intermediate in the synthesis of pharmacologically active benzodioxole derivatives. The reactive carbonyl fluoride group enables efficient amide bond formation with various nucleophiles, making it valuable for medicinal chemistry applications. Researchers utilize this compound to develop novel CNS-active molecules due to the blood-brain barrier permeability often associated with the benzodioxole scaffold. It’s particularly useful in PET tracer development where fluorine-18 labeling is required. The compound also finds application in materials science for creating specialized polymers with unique electronic properties.

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