Atomfair

Awaiting product image

Atomfair Benzene, 1-bromo-4-(trifluoromethyl)- 4-Bromobenzotrifluoride C7H4BrF3

Description 1-Bromo-4-(trifluoromethyl)benzene (CAS No. 402-43-7) is a high-purity aromatic compound with the molecular formula C7H4BrF3. This halogenated benzene derivative features a bromine substituent and a trifluoromethyl group in the para position, making it a versatile intermediate in organic synthesis and pharmaceutical research. Its unique electronic properties and stability under various reaction conditions make it ideal for cross-coupling reactions, such as Suzuki-Miyaura and Negishi couplings, as well as nucleophilic aromatic substitutions. Available in >98% purity, this compound is rigorously tested via GC/MS and NMR to ensure consistency for sensitive applications. Suitable for use in research laboratories, industrial R&D, and fine chemical…

Category:
Brands:

Description

Description

1-Bromo-4-(trifluoromethyl)benzene (CAS No. 402-43-7) is a high-purity aromatic compound with the molecular formula C7H4BrF3. This halogenated benzene derivative features a bromine substituent and a trifluoromethyl group in the para position, making it a versatile intermediate in organic synthesis and pharmaceutical research. Its unique electronic properties and stability under various reaction conditions make it ideal for cross-coupling reactions, such as Suzuki-Miyaura and Negishi couplings, as well as nucleophilic aromatic substitutions. Available in >98% purity, this compound is rigorously tested via GC/MS and NMR to ensure consistency for sensitive applications. Suitable for use in research laboratories, industrial R&D, and fine chemical manufacturing. Store in a cool, dry place under inert atmosphere to maintain stability.

  • CAS No: 402-43-7
  • Molecular Formula: C7H4BrF3
  • Molecular Weight: 225.01
  • Exact Mass: 223.94485
  • Monoisotopic Mass: 223.94485
  • IUPAC Name: 1-bromo-4-(trifluoromethyl)benzene
  • SMILES: C1=CC(=CC=C1C(F)(F)F)Br
  • Synonyms: 4-Bromobenzotrifluoride, 1-Bromo-4-(trifluoromethyl)benzene, Benzene, 1-bromo-4-(trifluoromethyl)-, EINECS 206-943-6, DTXSID0059950

Application

1-Bromo-4-(trifluoromethyl)benzene is widely used as a key building block in the synthesis of pharmaceuticals, agrochemicals, and liquid crystals. Its electron-withdrawing trifluoromethyl group enhances reactivity in palladium-catalyzed cross-coupling reactions, enabling the construction of complex aromatic systems. The compound also serves as a precursor for fluorinated materials in electronic and optical applications. Researchers leverage its stability and selectivity in nucleophilic substitution reactions to introduce functional groups into aromatic scaffolds.

If you are interested or have any questions, please contact us at support@atomfair.com