Description

Anisole (CAS 100-66-3) is a clear, colorless to pale yellow liquid with a pleasant, aromatic odor. This organic compound, with the molecular formula C₇H₈O, is classified as an aromatic ether, consisting of a methoxy group (–OCH₃) attached to a benzene ring. Anisole is widely utilized in organic synthesis, fragrance formulation, and as a solvent in various industrial and laboratory applications. It exhibits excellent solubility in organic solvents like ethanol and diethyl ether but is only slightly soluble in water. With a boiling point of 154°C and a melting point of -37°C, Anisole is stable under normal conditions but should be stored in a cool, well-ventilated area away from oxidizing agents.

Our high-purity Anisole (>99%) is rigorously tested for quality, ensuring low levels of impurities and consistent performance in sensitive applications. Available in various packaging options, from small laboratory vials to bulk quantities, this product is ideal for researchers, chemists, and manufacturers requiring a reliable aromatic ether for synthetic or analytical purposes.

Properties

• CAS Number: 100-66-3
• Complexity: 55.4
• IUPAC Name: anisole
• InChI: InChI=1S/C7H8O/c1-8-7-5-3-2-4-6-7/h2-6H,1H3
• InChI Key: RDOXTESZEPMUJZ-UHFFFAOYSA-N
• LogP: Log Kow = 2.11
• Exact Mass: 108.057514874
• Molecular Formula: C7H8O
• Molecular Weight: 108.14
• SMILES: COC1=CC=CC=C1
• Topological: 9.2
• Monoisotopic Mass: 108.057514874
• Physical Description: Anisole appears as a clear straw-colored liquid with an aromatic odor. Insoluble in water and the same density as water. Vapors heavier than air. Moderately toxic by ingestion. A skin irritant. Used to make perfumes, flavorings and as a solvent.
• Color/Form: MOBILE LIQUID, CLEAR STRAW COLOR
• Odor: SWEET ANISE-LIKE ODOR
• Taste: SWEET
• Boiling Point: 155.5 °C AT 760 MM HG
• Melting Point: -37.3 °C
• Flash Point: 125 °F
• Solubility: SOLUBLE IN ALCOHOL AND ETHER
• Density: 0.9956 AT 18 °C/4 °C
• Vapor Density: 3.72
• Vapor Pressure: 3.54 [mmHg]
• Autoignition Temperature: 887 °F
• Viscosity: 1.52 centipoise at 15 °C; 0.778 centipoise at 30 °C
• Heat of Combustion: -3783.12 kJ/mol @ 25 °C /liquid/
• Heat of Vaporization: 46.84 kJ/mol @ 25 °C
• Surface Tension: 36.18 dyne/cm @ 15 °C; 35.00 dyne/cm @ 20 °C; 34.15 dyne/cm @ 30 °C
• Refractive Index: INDEX OF REFRACTION: 1.51791 AT 20 °C/D
• Synonyms: ANISOLE, 100-66-3, Methyl phenyl ether, Anisol, Phenyl methyl ether, Phenoxymethane, Anizol, Phenol methyl ether, Ether, methyl phenyl, Benzene, methoxy, HSDB 44, methylphenyl ether, FEMA No. 2097, FEMA Number 2097, NSC 7920, UNII-B3W693GAZH, EINECS 202-876-1, B3W693GAZH, CHEBI:16579, AI3-00042, NSC-7920, DTXSID4041608, EC 202-876-1, ANISOLE (USP-RS), ANISOLE [USP-RS], FEMA NUMBER: 2097, DTXCID2021608, 202-876-1, Methoxybenzene, Benzene, methoxy-, Methoxy-Benzene, 4-methoxybenzene, Ether, methyl phenyl-, MFCD00008354, UN2222, anisole-, 4-methoxy benzene, Methyl phenyl-Ether, Anisole, 8CI, Methoxy-Benzeneanisole, ANISOLE [FHFI], ANISOLE [HSDB], ANISOLE [FCC], ANISOLE [MI], Methoxy-benzene (anisol), bmse010217, SCHEMBL1204, SCHEMBL1205, SCHEMBL1413, SCHEMBL2370, SCHEMBL2699, WLN: 1OR, Anisole, analytical standard, Anisole, anhydrous, 99.7%, SCHEMBL134989, SCHEMBL148512, SCHEMBL481022, SCHEMBL497674, CHEMBL278024, SCHEMBL1178888, SCHEMBL1387910, SCHEMBL1712973, SCHEMBL2874113, SCHEMBL2875823, SCHEMBL6000054, SCHEMBL7100899, SCHEMBL12015260, SCHEMBL15987729, Anisole, ReagentPlus(R), 99%, DTXSID10938426, NSC7920, CHEBI:192244, METHOXY-BENZENE (ANISOL), Methyl phenyl ether;Methoxybenzene, Anisole, >=99%, FCC, FG, BDBM50386177, STL263485, AKOS000120161, CCG-266043, FA47253, UN 2222, Anisole [UN2222] [Flammable liquid], MSK001105-1000M, LS-13275, DB-003588, A0492, NS00003297, EN300-16114, C01403, M03556, Methoxybenzene Solution in Methanol, 1000ug/mL, Q312244, Z53833865, F1908-0172, Anisole, United States Pharmacopeia (USP) Reference Standard, InChI=1/C7H8O/c1-8-7-5-3-2-4-6-7/h2-6H,1H, Anisole, Pharmaceutical Secondary Standard; Certified Reference Material

Application

Anisole is commonly employed as a precursor in the synthesis of perfumes, pharmaceuticals, and agrochemicals due to its reactive methoxy group. It serves as a versatile solvent in Grignard reactions and other organometallic processes. Additionally, Anisole is used as a flavoring agent in food industries and as a starting material for producing dyes and polymers.

Safety and Hazards

GHS Hazard Statements

• H226: Flammable liquid and vapor [Warning Flammable liquids]
• H402: Harmful to aquatic life [Hazardous to the aquatic environment, acute hazard]
• H412: Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]

Precautionary Statements

• P210, P233, P240, P241, P242, P243, P273, P280, P303+P361+P353, P370+P378, P403+P235, and P501

Hazard Classes and Categories

• Flam. Liq. 3 (> 99.9%)
• Skin Irrit. 2 (76.5%)
• Eye Irrit. 2A (78.1%)
• STOT SE 3 (13.1%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.