Description

Aminolevulinic Acid Hydrochloride (ALA HCl) is a highly purified, pharmaceutical-grade compound with the molecular formula C₅H₁₀ClNO₃ and CAS number 5451-09-2. This derivative of 5-aminolevulinic acid is widely used in photodynamic therapy (PDT), dermatology, and oncology due to its role as a precursor in the biosynthesis of heme and porphyrins. When applied topically or administered systemically, ALA HCl is metabolized into protoporphyrin IX (PpIX), a photosensitizer that accumulates preferentially in rapidly dividing cells, enabling targeted destruction under light exposure. Our product is rigorously tested for purity (≥98%) and consistency, ensuring optimal performance in clinical and research applications. Available as a white to off-white crystalline powder, it is soluble in water and compatible with standard laboratory protocols. Ideal for studies involving PDT, fluorescence-guided surgery, and cellular metabolism research.

Properties

• CAS Number: 5451-09-2
• Complexity: 121
• IUPAC Name: 5-amino-4-oxo-pentanoic acid;hydrochloride
• InChI: InChI=1S/C5H9NO3.ClH/c6-3-4(7)1-2-5(8)9;/h1-3,6H2,(H,8,9);1H
• InChI Key: ZLHFONARZHCSET-UHFFFAOYSA-N
• Exact Mass: 167.0349209
• Molecular Formula: C5H10ClNO3
• Molecular Weight: 167.59
• SMILES: C(CC(=O)O)C(=O)CN.Cl
• Topological: 80.4
• Monoisotopic Mass: 167.0349209
• Synonyms: 5-Aminolevulinic acid hydrochloride, 5451-09-2, Aminolevulinic acid hydrochloride, 5-Amino-4-oxopentanoic acid hydrochloride, Levulan Kerastick, delta-Aminolevulinic acid hydrochloride, Aminolevulinic Acid HCl, Ameluz, Alaglio, Alabel, 5-Aminolevulinate hydrochloride, AlaCare, Pentanoic acid, 5-amino-4-oxo-, hydrochloride, V35KBM8JGR, NSC-18509, NPC-07, DTXSID5045914, EINECS 226-679-5, UNII-V35KBM8JGR, NSC 18509, 5-aminolevulinic acid.HCl, 5-AMINO-4-OXOPENTANOIC ACID HCL, Levulinic acid, 5-amino-, hydrochloride, 5-Amino-3-oxopentanoic acid (hydrochloride), DTXCID3025914, CHEBI:132969, NSC18509, 4-carboxy-2-oxobutan-1-aminium chloride, AMINOLEVULINIC ACID HYDROCHLORIDE (MART.), AMINOLEVULINIC ACID HYDROCHLORIDE [MART.], AMINOLEVULINIC ACID HYDROCHLORIDE (USP-RS), AMINOLEVULINIC ACID HYDROCHLORIDE [USP-RS], AMINOLEVULINIC ACID HYDROCHLORIDE (USP MONOGRAPH), AMINOLEVULINIC ACID HYDROCHLORIDE [USP MONOGRAPH], Acid Hydrochloride, Aminolevulinic, Hydrochloride, Aminolevulinic Acid, delta-AMINOLEVULINIC ACID HCl, 5-Amino-4-oxopentanoic acid monohydrochloride, AMINOLEVULINIC ACID HYDROCHLORIDE COMPONENT OF SONALA001, AMINOLEVULINIC ACID HYDROCHLORIDE COMPONENT OF SONALA-001, 226-679-5, Levulan, Gliolan, 5-Aminolevulinic acid HCl, MFCD00012869, Gleolan, 5-Aminolevulinic acid (hydrochloride), 5-aminolevulinic acid hydrochloride salt, 5-Aminolevulinic acid, HCl, .delta.-Aminolevulinic acid hydrochloride, 5-Amino-4-oxopentanoic acid;hydrochloride, 5-AMINO-15N-LEVULINIC ACID HCL, 116571-80-3, (4-carboxy-2-oxobutyl)azanium;chloride, Aminolevulinic acid hydrochloride [USAN], NCGC00095111-01, d-Aminolevulinic acid hydrochloride, 5-amino-4-oxopentanoic acid hydrochloride;5-Amino-4-oxopentanoic acid, 5-amino-4-oxopentanoic acid, chloride, CAS-5451-09-2, 5-amino-levulinic acid hydrochloride, 5-Aminolevulinic acid hydrochloride, >=97.0% (AT), 5-Aminolaevulinic acid hydrochloride, Gleolan (TN), Levulan (TN), Ameluz (TN), ALA HCl, ALA-PDT, ALA;5-ALA, Pentanoic acid, hydrochloride, 5-amino-4-keto-valeric acid, SCHEMBL192308, SPECTRUM1504184, CHEMBL1200582, HMS1922F13, HMS5081O21, HMS6018G12, PD-P-506-A, Pharmakon1600-01504184, 5 ALA HCL (TRIVIAL NAME), BCP02161, HY-N0305, 5-amino levulinic acid hydrochloride, Tox21_111426, CCG-39079, NSC758687, SBB003880, AKOS015904495, Tox21_111426_1, AC-4252, BCP9000174, GS-3020, NSC-758687, NCGC00095111-02, NCGC00095111-03, NCGC00178086-03, 5451-09-2 (HCl), SY017972, DB-005367, 5-Aminolevulinic acid hydrochloride, >=98%, A0325, S2553, ST50824911, SW218068-2, Aminolevulinic acid hydrochloride (JAN/USAN), AMINOLEVULINIC ACID HYDROCHLORIDE [JAN], D02908, EN300-748883, AMINOLEVULINIC ACID HYDROCHLORIDE [WHO-DD], .DELTA.-AMINOLEVULINIC ACID HYDROCHLORIDE [MI], 5-AMINOLEVULINIC ACID HYDROCHLORIDE [EMA EPAR], AMINOLEVULINIC ACID HYDROCHLORIDE [ORANGE BOOK], Q27291473, Z1741972992, 0C1E43DB-1221-4963-BFA4-18D3170000A4, 5-Aminolevulinic acid hydrochloride, BioReagent, suitable for cell culture, powder, >=98%, Aminolevulinic Acid HCl; Aminolevulinic Acid hydrochloride;ALA; 5-ALA;Aminolevulinic acid, Aminolevulinic acid hydrochloride, United States Pharmacopeia (USP) Reference Standard

Aminolevulinic Acid Hydrochloride is primarily used in photodynamic therapy (PDT) for treating actinic keratosis, basal cell carcinoma, and other skin conditions. It also serves as a diagnostic tool in fluorescence-guided tumor resection, where it highlights malignant tissue under blue light. Researchers utilize ALA HCl to study porphyrin biosynthesis pathways and oxidative stress responses in cellular models. Its role in enhancing PpIX accumulation makes it valuable for investigating mitochondrial function and cancer therapeutics.

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