Description

8-Fluoroquinoline (CAS No. 394-68-3) is a high-purity fluorinated heterocyclic compound with the molecular formula C₉H₆FN. This specialized chemical is widely utilized in pharmaceutical research, agrochemical development, and material science due to its unique structural properties. As a fluorinated derivative of quinoline, it serves as a versatile building block for synthesizing bioactive molecules, ligands, and advanced materials. Our product is rigorously tested to ensure exceptional quality, with ≥98% purity (HPLC), and is supplied in sealed packaging under inert conditions to maintain stability. Ideal for researchers seeking reliable fluorinated intermediates for drug discovery, catalysis, or fluorescence studies.

Properties

• CAS Number: 394-68-3
• Complexity: 138
• IUPAC Name: 8-fluoroquinoline
• InChI: InChI=1S/C9H6FN/c10-8-5-1-3-7-4-2-6-11-9(7)8/h1-6H
• InChI Key: RNAAXKYOTPSFGV-UHFFFAOYSA-N
• Exact Mass: 147.048427358
• Molecular Formula: C9H6FN
• Molecular Weight: 147.15
• SMILES: C1=CC2=C(C(=C1)F)N=CC=C2
• Topological: 12.9
• Monoisotopic Mass: 147.048427358
• Synonyms: 8-Fluoroquinoline, Quinoline, 8-fluoro-, CCRIS 2891, WC3ZS5FY7R, BRN 0114548, NSC-51786, FLUOROQUINOLINE, 8-, DTXSID60192591, NSC 51786, DTXCID00115082, 807-825-2, 5-20-07-00311 (beilstein handbook reference), 394-68-3, MFCD01685514, NSC51786, 8-Fluoro-quinolinium, UNII-WC3ZS5FY7R, SCHEMBL855198, 8-Fluoroquinoline, AldrichCPR, SCHEMBL1538341, SCHEMBL1828122, SCHEMBL1926708, SCHEMBL4158158, SCHEMBL5801213, SCHEMBL6290789, CHEMBL1162366, SCHEMBL20264913, RNAAXKYOTPSFGV-UHFFFAOYSA-N, BCP19389, SBB059577, STL134906, AKOS005259248, AC-3295, CS-W001560, FF54377, PS-6513, SB67539, SY004608, F1185, NS00125050, ST51044523, EN300-27706, Z243277338

Application

8-Fluoroquinoline is a key intermediate in medicinal chemistry for the development of quinolone-based antibiotics and antiviral agents. Its fluorinated structure enhances binding affinity in drug-receptor interactions, making it valuable for pharmaceutical R&D. Additionally, it serves as a precursor in the synthesis of fluorescent dyes and ligands for transition metal catalysis. Researchers also employ this compound in agrochemical studies to investigate novel pesticidal and herbicidal compounds.

Safety and Hazards

GHS Hazard Statements

• H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H335 (96.8%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Skin Irrit. 2 (100%)
• Eye Irrit. 2A (100%)
• STOT SE 3 (96.8%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.