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Atomfair 7-Chloro-2-iodothieno(3,2-b)pyridine C7H3ClINS CAS 602303-26-4

7-Chloro-2-iodothieno[3,2-b]pyridine (CAS No. 602303-26-4) is a high-purity heterocyclic organic compound with the molecular formula C7H3ClINS . This specialized chemical features a thienopyridine core functionalized with chloro and iodo substituents, making it a valuable intermediate for pharmaceutical and materials science research. Its unique structure is ideal for cross-coupling reactions, such as Suzuki-Miyaura or Buchwald-Hartwig couplings, enabling the synthesis of complex bioactive molecules. Each batch undergoes rigorous QC testing (HPLC, NMR) to ensure ≥95% purity, meeting the stringent demands of medicinal chemistry and drug discovery applications. Available in amber vials under inert packaging to ensure stability.

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Description

7-Chloro-2-iodothieno[3,2-b]pyridine (CAS No. 602303-26-4) is a high-purity heterocyclic organic compound with the molecular formula C7H3ClINS. This specialized chemical features a thienopyridine core functionalized with chloro and iodo substituents, making it a valuable intermediate for pharmaceutical and materials science research. Its unique structure is ideal for cross-coupling reactions, such as Suzuki-Miyaura or Buchwald-Hartwig couplings, enabling the synthesis of complex bioactive molecules. Each batch undergoes rigorous QC testing (HPLC, NMR) to ensure ≥95% purity, meeting the stringent demands of medicinal chemistry and drug discovery applications. Available in amber vials under inert packaging to ensure stability.

Properties

  • CAS Number: 602303-26-4
  • Complexity: 157
  • IUPAC Name: 7-chloro-2-iodo-thieno[3,2-b]pyridine
  • InChI: InChI=1S/C7H3ClINS/c8-4-1-2-10-5-3-6(9)11-7(4)5/h1-3H
  • InChI Key: GYHAKTKQWPBADS-UHFFFAOYSA-N
  • Exact Mass: 294.87195
  • Molecular Formula: C7H3ClINS
  • Molecular Weight: 295.53
  • SMILES: C1=CN=C2C=C(SC2=C1Cl)I
  • Topological: 41.1
  • Monoisotopic Mass: 294.87195
  • Synonyms: 7-Chloro-2-iodothieno[3,2-b]pyridine, 602303-26-4, DTXSID00590491, 7-Chloro-2-iodothieno(3,2-b)pyridine, DTXCID90541255, 889-065-1, MFCD08448166, C7H3ClINS, THIENO[3,2-B]PYRIDINE, 7-CHLORO-2-IODO-, 7-chloro-2-iodo-thieno[3,2-b]pyridine, 2-Iodo-7-chlorothieno[3,2-b]pyridine, SCHEMBL108770, GYHAKTKQWPBADS-UHFFFAOYSA-N, CS-D1056, AKOS015851081, PB17532, AS-42150, SY034530, DB-014671, 7-Chloro-2-iodothieno[3 pound not2-b]pyridine, EN300-7375297

Application

7-Chloro-2-iodothieno[3,2-b]pyridine serves as a key building block in the synthesis of kinase inhibitors and other biologically active heterocycles. Its halogenated structure facilitates palladium-catalyzed cross-coupling reactions for drug candidate diversification. Researchers utilize this compound in the development of anticancer and antiviral agents targeting thienopyridine-based pharmacophores. It is also employed in materials science for constructing π-conjugated systems in organic electronics.

Safety and Hazards

GHS Hazard Statements

  • H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
  • H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
  • H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
  • H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

  • P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

  • Acute Tox. 4 (100%)
  • Skin Irrit. 2 (100%)
  • Eye Irrit. 2A (100%)
  • STOT SE 3 (100%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.

Disclaimer

Intended Use & Restrictions

This product is sold exclusively for laboratory research, analytical testing, or non-commercial purposes.

  • Strictly prohibited: Resale, repackaging, or formulation into commercial products.
  • Not approved for human/animal use, diagnostics, or manufacturing (including pharmaceuticals, agrochemicals, or consumer goods).

Patent & Regulatory Compliance

Certain molecules may be protected by active patents or regulatory restrictions.

  • Buyers must independently verify patent status (e.g., via USPTO/EPO/CNIPA) and comply with local laws.
  • Atomfair LLC does not provide legal assurances regarding patent non-infringement or jurisdictional compliance.

Liability Release

By purchasing, the buyer agrees to:

  • Use this product only as permitted by law.
  • Indemnify Atomfair LLC against all claims arising from misuse, patent infringement, or regulatory violations.

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