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Atomfair 7-Bromo-4-chlorothieno[3,2-d]pyrimidine C6H2BrClN2S

Description 7-Bromo-4-chlorothieno[3,2-d]pyrimidine (CAS No. 31169-27-4) is a high-purity heterocyclic compound with the molecular formula C6H2BrClN2S , widely utilized in pharmaceutical and agrochemical research. This thienopyrimidine derivative serves as a versatile building block for the synthesis of biologically active molecules, particularly in the development of kinase inhibitors and other therapeutic agents. Its unique structure, featuring both bromo and chloro substituents, allows for selective functionalization via cross-coupling reactions, making it invaluable in medicinal chemistry. Our product is rigorously tested to ensure ??95% purity (HPLC) and is supplied as a crystalline solid with detailed analytical data (NMR, MS) for quality assurance. Store under…

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Description

Description

7-Bromo-4-chlorothieno[3,2-d]pyrimidine (CAS No. 31169-27-4) is a high-purity heterocyclic compound with the molecular formula C6H2BrClN2S, widely utilized in pharmaceutical and agrochemical research. This thienopyrimidine derivative serves as a versatile building block for the synthesis of biologically active molecules, particularly in the development of kinase inhibitors and other therapeutic agents. Its unique structure, featuring both bromo and chloro substituents, allows for selective functionalization via cross-coupling reactions, making it invaluable in medicinal chemistry. Our product is rigorously tested to ensure ??95% purity (HPLC) and is supplied as a crystalline solid with detailed analytical data (NMR, MS) for quality assurance. Store under inert conditions at 2-8??C to maintain stability.

  • CAS No: 31169-27-4
  • Molecular Formula: C6H2BrClN2S
  • Molecular Weight: 249.52
  • Exact Mass: 247.88106
  • Monoisotopic Mass: 247.88106
  • IUPAC Name: 7-bromo-4-chlorothieno[3,2-d]pyrimidine
  • SMILES: C1=C(C2=C(S1)C(=NC=N2)Cl)Br
  • Synonyms: 7-Bromo-4-chlorothieno[3,2-d]pyrimidine, 31169-27-4, MFCD08273917, 7-Bromo-4-chloro-thieno[3,2-d]pyrimidine, Thieno[3,2-d]pyrimidine, 7-bromo-4-chloro-

Application

7-Bromo-4-chlorothieno[3,2-d]pyrimidine is a key intermediate in the synthesis of kinase inhibitors targeting cancer and inflammatory diseases. Its reactive halogen sites enable Suzuki-Miyaura and Buchwald-Hartwig couplings for structure-activity relationship (SAR) studies. Researchers also employ it to develop fluorescent probes for cellular imaging due to its rigid heterocyclic core. The compound’s thienopyrimidine scaffold is frequently explored in fragment-based drug design for antimicrobial applications.

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