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Atomfair 6-(Trifluoromethyl)pyridine-2-carboxylic acid C7H4F3NO2

Description 6-(Trifluoromethyl)pyridine-2-carboxylic acid (CAS No. 131747-42-7) is a high-purity fluorinated pyridine derivative with the molecular formula C7H4F3NO2. This compound features a trifluoromethyl group at the 6-position and a carboxylic acid moiety at the 2-position of the pyridine ring, making it a versatile building block for pharmaceutical, agrochemical, and material science applications. Its unique electronic and steric properties enhance reactivity in cross-coupling, nucleophilic substitution, and metal-catalyzed reactions. Available in ??98% purity (HPLC), it is supplied as a white to off-white crystalline powder with excellent batch-to-batch consistency. Store under inert conditions at 2-8??C to ensure long-term stability. Suitable for research, process development,…

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Description

Description

6-(Trifluoromethyl)pyridine-2-carboxylic acid (CAS No. 131747-42-7) is a high-purity fluorinated pyridine derivative with the molecular formula C7H4F3NO2. This compound features a trifluoromethyl group at the 6-position and a carboxylic acid moiety at the 2-position of the pyridine ring, making it a versatile building block for pharmaceutical, agrochemical, and material science applications. Its unique electronic and steric properties enhance reactivity in cross-coupling, nucleophilic substitution, and metal-catalyzed reactions. Available in ??98% purity (HPLC), it is supplied as a white to off-white crystalline powder with excellent batch-to-batch consistency. Store under inert conditions at 2-8??C to ensure long-term stability. Suitable for research, process development, and scale-up synthesis.

  • CAS No: 131747-42-7
  • Molecular Formula: C7H4F3NO2
  • Molecular Weight: 191.11
  • Exact Mass: 191.01941286
  • Monoisotopic Mass: 191.01941286
  • IUPAC Name: 6-(trifluoromethyl)pyridine-2-carboxylic acid
  • SMILES: C1=CC(=NC(=C1)C(F)(F)F)C(=O)O
  • Synonyms: 131747-42-7, 6-(Trifluoromethyl)pyridine-2-carboxylic acid, 6-trifluoromethyl-2-pyridinecarboxylic acid, DTXSID30563698, DTXCID40514474

Application

6-(Trifluoromethyl)pyridine-2-carboxylic acid is widely used as a key intermediate in the synthesis of bioactive molecules, particularly in the development of pharmaceuticals and agrochemicals. Its trifluoromethyl group enhances metabolic stability and lipophilicity, making it valuable in drug discovery for CNS and antiviral agents. The compound also serves as a ligand precursor in catalysis and a monomer for specialty polymers with tailored electronic properties.

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