Description

6-(Morpholino)pyridine-3-boronic Acid (contains varying amounts of Anhydride) is a high-purity boronic acid derivative with the molecular formula C₉H₁₃BN₂O₃ and CAS number 904326-93-8. This compound, also known by its IUPAC name (6-morpholin-4-ylpyridin-3-yl)boronic acid, is a valuable building block in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions. The product may contain varying amounts of anhydride, which should be considered during experimental planning. It is supplied as a fine powder or crystalline solid, ensuring optimal handling and solubility for research applications. Suitable for use in pharmaceutical, agrochemical, and materials science research, this boronic acid derivative is rigorously tested for quality and consistency. Store in a cool, dry place under inert atmosphere to maintain stability.

Properties

• CAS Number: 904326-93-8
• Complexity: 200
• IUPAC Name: (6-morpholino-3-pyridyl)boronic acid
• InChI: InChI=1S/C9H13BN2O3/c13-10(14)8-1-2-9(11-7-8)12-3-5-15-6-4-12/h1-2,7,13-14H,3-6H2
• InChI Key: FFPQELNXDVTLEW-UHFFFAOYSA-N
• Exact Mass: 208.1019224
• Molecular Formula: C9H13BN2O3
• Molecular Weight: 208.02
• SMILES: B(C1=CN=C(C=C1)N2CCOCC2)(O)O
• Topological: 65.8
• Monoisotopic Mass: 208.1019224
• Synonyms: 6-(Morpholino)pyridine-3-boronic Acid (contains varying amounts of Anhydride), 801-717-9, 904326-93-8, 6-morpholinopyridin-3-ylboronic acid, (6-Morpholinopyridin-3-yl)boronic acid, 6-MORPHOLINOPYRIDINE-3-BORONIC ACID, (6-Morpholin-4-Ylpyridin-3-Yl)Boronic Acid, 6-Morpholino-3-pyridineboronic Acid, 6-(4-MORPHOLINYL)-3-PYRIDINYLBORONIC ACID, 2-MORPHOLINO-5-PYRIDINEBORONIC ACID, [6-(4-morpholinyl)-3-pyridinyl]boronic acid, MFCD03086116, [6-(Morpholin-4-yl)pyridin-3-yl]boronic acid, 6-morpholinopyridin-3-yl-3-boronic acid, SCHEMBL9147, DTXSID40673757, FFPQELNXDVTLEW-UHFFFAOYSA-N, BBL101092, STL554886, 2-morpholino-5-pyridine boronic acid, AKOS000283803, 6-(Morpholino)pyridine-3-boronic acid, AB13113, AC-8558, 2-(morpholino)pyridin-5-ylboronic acid, AS-47476, BP-12069, SY022331, DB-031960, CS-0097753, M2967, 2-(MORPHOLINO)PYRIDINE-5-BORONIC ACID, 6-(4-Morpholin-1-yl)pyridin-3-ylboronic acid, F13868, A843548, 6-Morpholinopyridine-3-boronic acid (contains varying amounts of Anhydride)

Application

6-(Morpholino)pyridine-3-boronic Acid is widely used as a key intermediate in Suzuki-Miyaura cross-coupling reactions to form biaryl compounds. Its morpholine and pyridine moieties make it particularly useful in the synthesis of pharmaceuticals and agrochemicals. Researchers also employ this compound in the development of novel materials, such as organic semiconductors and metal-organic frameworks (MOFs). Its boronic acid functionality allows for further derivatization, enabling the creation of complex molecular architectures. This reagent is especially valuable in medicinal chemistry for the construction of drug-like scaffolds.

Safety and Hazards

GHS Hazard Statements

• H302 (50%): Harmful if swallowed [Warning Acute toxicity, oral]
• H315 (50%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (50%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]

Precautionary Statements

• P264, P264+P265, P270, P280, P301+P317, P302+P352, P305+P351+P338, P321, P330, P332+P317, P337+P317, P362+P364, and P501

Hazard Classes and Categories

• Skin Irrit. 2 (50%)
• Eye Irrit. 2 (50%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.