Description

Description

6-(Methoxycarbonyl)pyridine-3-boronic acid (CAS: 1072945-86-8) is a high-purity boronic acid derivative with the molecular formula C₇H₈BNO₄, widely used in Suzuki-Miyaura cross-coupling reactions and other palladium-catalyzed transformations. This compound features a pyridine ring substituted with a methoxycarbonyl group at the 6-position and a boronic acid moiety at the 3-position, making it a versatile building block for pharmaceutical and materials science research. It is supplied as a white to off-white crystalline powder with ??95% purity (HPLC), ensuring optimal performance in synthetic applications. Proper storage under inert conditions (2-8??C, argon) is recommended to maintain stability. Ideal for researchers developing novel heterocyclic compounds, catalysts, or bioactive molecules.

Application

6-(Methoxycarbonyl)pyridine-3-boronic acid is a key intermediate in the synthesis of pharmaceuticals, agrochemicals, and functional materials via Suzuki-Miyaura couplings. It enables the introduction of pyridine-carboxylate motifs into complex molecules, enhancing drug-like properties such as solubility and binding affinity. Researchers also utilize it to construct conjugated polymers for optoelectronic applications. Its reactivity with aryl halides under mild conditions makes it valuable for combinatorial chemistry and high-throughput screening.

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