Description

6-Hydroxy-2-naphthonitrile (CAS No. 52927-22-7) is a high-purity organic compound with the molecular formula C₁₁H₇NO. Also known as 6-hydroxynaphthalene-2-carbonitrile (IUPAC name), this specialized chemical is a valuable intermediate in organic synthesis and materials science. The compound features a hydroxyl group and a nitrile group attached to a naphthalene backbone, offering versatile reactivity for further functionalization.

Our product is rigorously tested for purity and consistency, making it ideal for research applications in pharmaceuticals, agrochemicals, and advanced material development. It is supplied as a fine crystalline powder with excellent solubility in common organic solvents such as DMF, DMSO, and ethanol. Each batch is accompanied by comprehensive analytical data including HPLC, NMR, and MS spectra to ensure quality and reproducibility for your experiments.

Store in a cool, dry place away from light and moisture to maintain stability. Suitable for use in coupling reactions, heterocyclic synthesis, and as a precursor for fluorescent dyes or liquid crystal materials.

Properties

• CAS Number: 52927-22-7
• Complexity: 229
• IUPAC Name: 6-hydroxynaphthalene-2-carbonitrile
• InChI: InChI=1S/C11H7NO/c12-7-8-1-2-10-6-11(13)4-3-9(10)5-8/h1-6,13H
• InChI Key: WKTNIBWKHNIPQR-UHFFFAOYSA-N
• Exact Mass: 169.052763847
• Molecular Formula: C11H7NO
• Molecular Weight: 169.18
• SMILES: C1=CC2=C(C=CC(=C2)O)C=C1C#N
• Topological: 44
• Monoisotopic Mass: 169.052763847
• Synonyms: 6-Hydroxy-2-naphthonitrile, 628-663-7, 6-Cyano-2-naphthol, 52927-22-7, 6-hydroxynaphthalene-2-carbonitrile, 2-Naphthalenecarbonitrile, 6-hydroxy-, 6-Hydroxy-naphthalene-2-carbonitrile, MFCD01863480, 2-Cyano-6-hydroxynaphthalene, 2-hydroxy-6-cyanonaphthalene, 6-Cyano-2-naphthol, 97%, SCHEMBL1028464, DTXSID90404614, 6-hydroxy-2-naphthalenecarbonitrile, ALBB-026636, SBB059370, AKOS015836114, AC-6788, CS-W002854, FS-2638, 58200-90-1, SY021503, DB-052211, H0995, ST51044396, EN300-1615122

Application

6-Hydroxy-2-naphthonitrile serves as a key intermediate in the synthesis of pharmaceuticals, particularly for developing kinase inhibitors and anti-inflammatory agents. Its reactive hydroxyl and nitrile groups enable facile derivatization for constructing complex heterocycles in medicinal chemistry. Researchers also utilize this compound in material science for designing organic semiconductors and fluorescent probes due to its conjugated naphthalene core. Additionally, it finds application in agrochemical research as a building block for crop protection agents.

Safety and Hazards

GHS Hazard Statements

• H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H335 (97.7%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Skin Irrit. 2 (100%)
• Eye Irrit. 2 (100%)
• STOT SE 3 (97.7%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.