Description

Description

6-Fluoro-2-methylquinoline (CAS No. 1128-61-6) is a high-purity fluorinated quinoline derivative with the molecular formula C₁₀H₈FN. This heterocyclic aromatic compound features a fluorine substituent at the 6-position and a methyl group at the 2-position of the quinoline backbone, offering unique electronic and steric properties for advanced synthetic applications. Ideal for pharmaceutical research, material science, and agrochemical development, this compound is rigorously tested for consistency (??95% purity by HPLC) and supplied in sealed, light-resistant packaging to ensure stability. Its well-defined structure (IUPAC: 6-fluoro-2-methylquinoline) makes it a valuable intermediate for Suzuki couplings, palladium-catalyzed cross-couplings, and other C?CH functionalization reactions. Store under inert conditions at 2?C8??C to maintain optimal quality.

Application

6-Fluoro-2-methylquinoline serves as a versatile building block in medicinal chemistry for the synthesis of fluorinated quinoline-based drug candidates, particularly antimicrobial and anticancer agents. Its electron-withdrawing fluorine moiety enhances binding affinity in target interactions, while the methyl group improves metabolic stability. Researchers also utilize it in OLED material development to modulate electron transport properties. In agrochemicals, it acts as a precursor for novel pesticides with improved environmental persistence.

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