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Atomfair 6-Chloropyridine-3-carbaldehyde 6-Chloronicotinaldehyde C6H4ClNO CAS 23100-12-1

6-Chloropyridine-3-carbaldehyde (CAS No. 23100-12-1) is a high-purity chlorinated pyridine derivative with the molecular formula C6H4ClNO . This compound is a versatile heterocyclic aldehyde , widely utilized as a key intermediate in pharmaceutical synthesis, agrochemical production, and materials science research. Its reactive aldehyde group and chlorine substitution at the 6-position enable selective functionalization, making it valuable for cross-coupling reactions , nucleophilic additions , and Schiff base formation . Available in >98% purity (GC), this product is supplied as a crystalline solid with strict quality control to ensure consistency in sensitive applications. Store under inert conditions at 2-8°C to prevent degradation. Suitable…

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Description

6-Chloropyridine-3-carbaldehyde (CAS No. 23100-12-1) is a high-purity chlorinated pyridine derivative with the molecular formula C6H4ClNO. This compound is a versatile heterocyclic aldehyde, widely utilized as a key intermediate in pharmaceutical synthesis, agrochemical production, and materials science research. Its reactive aldehyde group and chlorine substitution at the 6-position enable selective functionalization, making it valuable for cross-coupling reactions, nucleophilic additions, and Schiff base formation.

Available in >98% purity (GC), this product is supplied as a crystalline solid with strict quality control to ensure consistency in sensitive applications. Store under inert conditions at 2-8°C to prevent degradation. Suitable for HPLC, NMR, and LC-MS analysis. Hazard codes: H302-H315-H319-H335. SDS available upon request.

Properties

  • CAS Number: 23100-12-1
  • Complexity: 107
  • IUPAC Name: 6-chloropyridine-3-carbaldehyde
  • InChI: InChI=1S/C6H4ClNO/c7-6-2-1-5(4-9)3-8-6/h1-4H
  • InChI Key: AFWWKZCPPRPDQK-UHFFFAOYSA-N
  • Exact Mass: 140.9981414
  • Molecular Formula: C6H4ClNO
  • Molecular Weight: 141.55
  • SMILES: C1=CC(=NC=C1C=O)Cl
  • Topological: 30
  • Monoisotopic Mass: 140.9981414
  • Synonyms: 6-chloropyridine-3-carbaldehyde, 627-646-1, 6-Chloronicotinaldehyde, 23100-12-1, 2-chloropyridine-5-carbaldehyde, 6-Chloropyridine-3-carboxaldehyde, 2-Chloropyridine-5-carboxaldehyde, 3-Pyridinecarboxaldehyde, 6-chloro-, 2-chloro-5-formylpyridine, 6-Chloro-pyridine-3-carbaldehyde, 6-Chloro-3-pyridinecarboxaldehyde, 2-Chloro-5-pyridinecarboxaldehyde, MFCD03095223, 6-chloro-nicotinaldehyde, 6-chloronicotinic aldehyde, 6-Chloronicotinic aldehide, 6-chloropyridine-3-aldehyde, SCHEMBL453852, SCHEMBL453853, 6-Chloropyridin-3-carbaldehyde, 2-chloro-5-pyridinecarbaldehyde, 6-Chloro-3-pyridinecarbaldehyde, 6-chloro-pyridin-3-carbaldehyde, CHEMBL2228157, DTXSID10377270, (6-chloro-3-pyridyl)formaldehyde, (6-chloropyridin-3-yl)-methanone, 6-chloro-pyridine-3-carboxaldehyde, (6-chloro-pyridin-3-yl)-methanone, BCP22155, CS-B0848, BBL102417, BDBM50486230, CX1055, SBB004157, STL556219, AKOS005070535, 5L-349S, AC-6150, PB18586, 6-Chloropyridine-3-carboxaldehyde, 96%, SY017266, C2519, EN300-99381

Application

6-Chloropyridine-3-carbaldehyde serves as a critical building block in the synthesis of antiviral agents and herbicides. Its aldehyde group facilitates the preparation of imidazopyridine scaffolds in medicinal chemistry. Researchers employ it in palladium-catalyzed cross-coupling to construct complex heterocycles. The compound is also used to develop ligands for catalysis and photoactive materials.

Safety and Hazards

GHS Hazard Statements

  • H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
  • H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
  • H335 (97.8%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

  • P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

  • Skin Irrit. 2 (100%)
  • Eye Irrit. 2 (100%)
  • STOT SE 3 (97.8%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.

Disclaimer

Intended Use & Restrictions

This product is sold exclusively for laboratory research, analytical testing, or non-commercial purposes.

  • Strictly prohibited: Resale, repackaging, or formulation into commercial products.
  • Not approved for human/animal use, diagnostics, or manufacturing (including pharmaceuticals, agrochemicals, or consumer goods).

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Certain molecules may be protected by active patents or regulatory restrictions.

  • Buyers must independently verify patent status (e.g., via USPTO/EPO/CNIPA) and comply with local laws.
  • Atomfair LLC does not provide legal assurances regarding patent non-infringement or jurisdictional compliance.

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  • Use this product only as permitted by law.
  • Indemnify Atomfair LLC against all claims arising from misuse, patent infringement, or regulatory violations.

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