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Atomfair (6-Chloropyridin-3-yl)methanol C6H6ClNO CAS 21543-49-7

(6-Chloropyridin-3-yl)methanol (CAS No. 21543-49-7) is a high-purity organic compound with the molecular formula C6H6ClNO . This chlorinated pyridine derivative features a hydroxymethyl group at the 3-position, making it a versatile intermediate for pharmaceutical, agrochemical, and material science research. With a molecular weight of 143.57 g/mol, it is supplied as a white to off-white crystalline solid with ≥98% purity (HPLC). Ideal for nucleophilic substitution reactions, cross-coupling reactions, and as a precursor for heterocyclic synthesis. Store under inert conditions at 2-8°C to ensure stability. Available in research quantities (100mg to 10kg) with optional custom packaging.

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Description

(6-Chloropyridin-3-yl)methanol (CAS No. 21543-49-7) is a high-purity organic compound with the molecular formula C6H6ClNO. This chlorinated pyridine derivative features a hydroxymethyl group at the 3-position, making it a versatile intermediate for pharmaceutical, agrochemical, and material science research. With a molecular weight of 143.57 g/mol, it is supplied as a white to off-white crystalline solid with ≥98% purity (HPLC). Ideal for nucleophilic substitution reactions, cross-coupling reactions, and as a precursor for heterocyclic synthesis. Store under inert conditions at 2-8°C to ensure stability. Available in research quantities (100mg to 10kg) with optional custom packaging.

Properties

  • CAS Number: 21543-49-7
  • Complexity: 89.1
  • IUPAC Name: (6-chloro-3-pyridyl)methanol
  • InChI: InChI=1S/C6H6ClNO/c7-6-2-1-5(4-9)3-8-6/h1-3,9H,4H2
  • InChI Key: GOXYBEXWMJZLJB-UHFFFAOYSA-N
  • Exact Mass: 143.0137915
  • Molecular Formula: C6H6ClNO
  • Molecular Weight: 143.57
  • SMILES: C1=CC(=NC=C1CO)Cl
  • Topological: 33.1
  • Monoisotopic Mass: 143.0137915
  • Synonyms: 21543-49-7, (6-chloropyridin-3-yl)methanol, DTXSID20175880, DTXCID7098371, 628-017-4, 2-Chloro-5-hydroxymethylpyridine, 2-Chloro-5-(hydroxymethyl)pyridine, 6-Chloro-3-pyridinemethanol, 2-Chloro-5-pyridinemethanol, (6-Chloro-3-pyridinyl)methanol, 3-PYRIDINEMETHANOL, 6-CHLORO-, 6-Chloropyridine-3-methanol, MFCD01075226, 6-chloro-3-pyridylmethanol, 5-hydroxymethyl-2-chloropyridine, (6-chloro-3-pyridyl)methanol, 6-CHLORO-3-(HYDROXYMETHYL)PYRIDINE, 6-chloro-3-pyridinecarbinol, XD33A4CCQ8, 6-chloro-3-pyridine methanol, 6-chloro-3-pyridine-carbinol, 6-chloro-3-pyridine-methanol, 6-chloro-pyridine-3-methanol, SCHEMBL451490, SCHEMBL453717, (6-chloro-3-pyridyl)methan-1-ol, BCP33399, 2-chloro-5-(hydroxymethyl) pyridine, CL0081, SBB054780, AKOS005070664, 5L-348S, AC-2918, CS-W002737, FC04059, PB17199, 2-Chloro-5-hydroxymethylpyridine, 98%, BP-10161, SY003337, DB-013023, C1897, EN300-75761, (6-chloropyridin-3-yl)methanol;2-Chloro-5-pyridinemethanol

Application

(6-Chloropyridin-3-yl)methanol is widely used as a key intermediate in the synthesis of neonicotinoid insecticides such as imidacloprid. It serves as a building block for pharmaceutical candidates targeting CNS disorders due to its pyridine scaffold. The compound is also employed in metal-organic framework (MOF) research for ligand functionalization.

Safety and Hazards

GHS Hazard Statements

  • H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
  • H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
  • H335 (97.9%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

  • P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

  • Skin Irrit. 2 (100%)
  • Eye Irrit. 2 (100%)
  • STOT SE 3 (97.9%)

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.

Disclaimer

Intended Use & Restrictions

This product is sold exclusively for laboratory research, analytical testing, or non-commercial purposes.

  • Strictly prohibited: Resale, repackaging, or formulation into commercial products.
  • Not approved for human/animal use, diagnostics, or manufacturing (including pharmaceuticals, agrochemicals, or consumer goods).

Patent & Regulatory Compliance

Certain molecules may be protected by active patents or regulatory restrictions.

  • Buyers must independently verify patent status (e.g., via USPTO/EPO/CNIPA) and comply with local laws.
  • Atomfair LLC does not provide legal assurances regarding patent non-infringement or jurisdictional compliance.

Liability Release

By purchasing, the buyer agrees to:

  • Use this product only as permitted by law.
  • Indemnify Atomfair LLC against all claims arising from misuse, patent infringement, or regulatory violations.

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