Description

6-Chloro-5-methylpyridin-3-amine (CAS No. 38186-82-2) is a high-purity organic compound with the molecular formula C₆H₇ClN₂. This specialized chemical, also known as 5-Amino-2-chloro-3-picoline, is a valuable intermediate in pharmaceutical and agrochemical synthesis. The compound features a pyridine ring substituted with chloro, methyl, and amino functional groups, offering versatile reactivity for heterocyclic chemistry applications.

Our product is synthesized under strict quality control measures to ensure >98% purity (HPLC), with comprehensive analytical data including ¹H NMR, ¹³C NMR, and mass spectrometry available. The material is supplied as a crystalline solid with excellent shelf stability when stored under recommended conditions (2-8°C in airtight containers).

This building block is particularly useful for medicinal chemistry research, serving as a precursor for the development of novel drug candidates, especially in the synthesis of kinase inhibitors and other biologically active nitrogen-containing heterocycles.

Properties

• CAS Number: 38186-82-2
• Complexity: 97.1
• IUPAC Name: 6-chloro-5-methyl-pyridin-3-amine
• InChI: InChI=1S/C6H7ClN2/c1-4-2-5(8)3-9-6(4)7/h2-3H,8H2,1H3
• InChI Key: VSBISZPNLZFTPG-UHFFFAOYSA-N
• Exact Mass: 142.0297759
• Molecular Formula: C6H7ClN2
• Molecular Weight: 142.58
• SMILES: CC1=CC(=CN=C1Cl)N
• Topological: 38.9
• Monoisotopic Mass: 142.0297759
• Synonyms: 6-Chloro-5-methylpyridin-3-amine, 38186-82-2, 5-Amino-2-chloro-3-picoline, 2-Chloro-3-methyl-5-aminopyridine, 5-Amino-2-chloro-3-methylpyridine, MFCD03095087, 6-Chloro-5-methyl-pyridin-3-ylamine, 3-Pyridinamine, 6-chloro-5-methyl-, SCHEMBL1156177, DTXSID10485485, VSBISZPNLZFTPG-UHFFFAOYSA-N, 6-chloro-5-methyl-3-pyridylamine, SBB051914, AKOS005258273, AB13470, PS-5094, SB18614, AC-23036, SY028363, 5-Amino-2-chloro-3-methylpyridine, 97%, 6-CHLORO-5-METHYLPYRIDINE-3-AMINE, DB-013220, A2564, A6477, A6480, CS-0007524, EN300-88328

Application

6-Chloro-5-methylpyridin-3-amine serves as a key intermediate in pharmaceutical research, particularly in the synthesis of kinase inhibitors and other nitrogen-containing bioactive compounds. The compound’s reactive amino and chloro groups make it valuable for palladium-catalyzed coupling reactions in medicinal chemistry. Researchers utilize this building block in the development of novel heterocyclic scaffolds for drug discovery programs. Its structural features also make it suitable for agrochemical applications in crop protection agent development.

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