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Atomfair 6-Chloro-3-pyridinecarbonitrile 6-Chloronicotinonitrile C6H3ClN2

Description 6-Chloro-3-pyridinecarbonitrile (CAS No. 33252-28-7) is a high-purity organic compound with the molecular formula C6H3ClN2, widely utilized in pharmaceutical and agrochemical research. This heterocyclic nitrile derivative, also known by its IUPAC name 6-chloropyridine-3-carbonitrile , features a chloro-substituted pyridine ring with a cyano functional group at the 3-position, making it a versatile intermediate for nucleophilic substitution and cross-coupling reactions. Available in crystalline solid form, it is characterized by excellent stability under standard laboratory conditions. Ideal for use in Suzuki-Miyaura, Buchwald-Hartwig, and other palladium-catalyzed transformations, this compound is rigorously tested via HPLC, GC, and NMR to ensure ??98% purity, meeting the stringent…

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Description

Description

6-Chloro-3-pyridinecarbonitrile (CAS No. 33252-28-7) is a high-purity organic compound with the molecular formula C6H3ClN2, widely utilized in pharmaceutical and agrochemical research. This heterocyclic nitrile derivative, also known by its IUPAC name 6-chloropyridine-3-carbonitrile, features a chloro-substituted pyridine ring with a cyano functional group at the 3-position, making it a versatile intermediate for nucleophilic substitution and cross-coupling reactions. Available in crystalline solid form, it is characterized by excellent stability under standard laboratory conditions. Ideal for use in Suzuki-Miyaura, Buchwald-Hartwig, and other palladium-catalyzed transformations, this compound is rigorously tested via HPLC, GC, and NMR to ensure ??98% purity, meeting the stringent requirements of synthetic chemists and process development teams.

  • CAS No: 33252-28-7
  • Molecular Formula: C6H3ClN2
  • Molecular Weight: 138.55
  • Exact Mass: 137.9984758
  • Monoisotopic Mass: 137.9984758
  • IUPAC Name: 6-chloropyridine-3-carbonitrile
  • SMILES: C1=CC(=NC=C1C#N)Cl
  • Synonyms: 6-Chloronicotinonitrile, 6-Chloro-3-pyridinecarbonitrile, 608-851-5, 2-Chloro-5-cyanopyridine, 33252-28-7

Application

6-Chloro-3-pyridinecarbonitrile serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for antiviral and antihypertensive agents. It is also employed in the development of neonicotinoid insecticides due to its pyridine core. Researchers value its reactivity in palladium-catalyzed C?CN bond formations and cyanation reactions for functionalized heterocycles. Additionally, it finds use in material science for constructing nitrogen-rich molecular scaffolds.

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