Description

6-Bromopyridine-2-carboxylic acid (CAS No. 21190-87-4) is a high-purity brominated pyridine derivative with the molecular formula C₆H₄BrNO₂. This compound, also known as 6-Bromopicolinic acid, is a versatile building block in organic synthesis and pharmaceutical research. It features a carboxylic acid functional group at the 2-position and a bromine substituent at the 6-position of the pyridine ring, enabling diverse reactivity for cross-coupling reactions, metal-catalyzed transformations, and heterocyclic scaffold construction. Our product is rigorously tested for quality, with ≥95% purity (HPLC), and is supplied as a white to off-white crystalline powder. Ideal for researchers in medicinal chemistry, agrochemical development, and material science, this compound is packaged under inert conditions to ensure stability and longevity. Available in quantities ranging from milligrams to kilograms, with custom synthesis options upon request.

Properties

• CAS Number: 21190-87-4
• Complexity: 140
• IUPAC Name: 6-bromopyridine-2-carboxylic acid
• InChI: InChI=1S/C6H4BrNO2/c7-5-3-1-2-4(8-5)6(9)10/h1-3H,(H,9,10)
• InChI Key: XURXQNUIGWHWHU-UHFFFAOYSA-N
• Exact Mass: 200.94254
• Molecular Formula: C6H4BrNO2
• Molecular Weight: 202.01
• SMILES: C1=CC(=NC(=C1)Br)C(=O)O
• Topological: 50.2
• Monoisotopic Mass: 200.94254
• Synonyms: 6-bromopyridine-2-carboxylic acid, 628-217-1, 6-Bromopicolinic acid, 21190-87-4, 6-Bromo-2-pyridinecarboxylic acid, 2-Pyridinecarboxylic acid, 6-bromo-, 2-BROMO-6-PYRIDINECARBOXYLIC ACID, MFCD00093197, 2-bromo pyridine-6-carboxylic acid, 6-Bromo-pyridine-2-carboxylic acid, 6-Bromo-2-Pyridine Carboxylic Acid, 2-bromopyridine-6-carboxylic acid, 6-Bromopyridine-2-carboxylicacid, 6-Bromo-picolinic acid, 6-bromo-2-carboxypyridine, 6-bromo-2-picolinic acid, SCHEMBL4989, AC-907/30003051, CHEMBL1650603, 6-Bromo-2-pyridinecarboxylicacid, DTXSID90344021, 6-bromo-pyridin-2-carboxylic acid, 2-Bromo-6-pyridine-carboxylic acid, 6-bromopyridine-2- carboxylic acid, ALBB-022487, BCP22166, STR06958, GEO-00565, SBB003525, AKOS000279088, AB03328, AC-1244, CS-W009049, PS-4082, SB10171, 6-Bromopyridine-2-carboxylic acid, 98%, SY004392, DB-011848, DB-027828, B3024, ST51038481, EN300-40905, 6-Bromopyridine-2-carboxylic acid;6-Bromopicolinic acid, F0001-0756, Z415628156

Application

6-Bromopyridine-2-carboxylic acid serves as a key intermediate in the synthesis of pharmaceuticals, ligands for catalysis, and functionalized pyridine derivatives. It is widely used in Suzuki-Miyaura and Buchwald-Hartwig coupling reactions to construct complex heterocycles. Researchers employ this compound in the development of enzyme inhibitors, receptor modulators, and metal-organic frameworks (MOFs). Its bromine substituent facilitates further functionalization, while the carboxylic acid group allows for conjugation or salt formation.

Safety and Hazards

GHS Hazard Statements

• H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H335 (97.9%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Skin Irrit. 2 (100%)
• Eye Irrit. 2 (100%)
• STOT SE 3 (97.9%)

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.