Description

Description

6-Bromopyridine-2-carboxylic acid (CAS No. 21190-87-4) is a high-purity brominated pyridine derivative with the molecular formula C₆H₄BrNO₂. This compound, also known as 6-Bromopicolinic acid, is a versatile building block in organic synthesis and pharmaceutical research. It features a carboxylic acid functional group at the 2-position and a bromine substituent at the 6-position of the pyridine ring, enabling diverse reactivity for cross-coupling reactions, metal-catalyzed transformations, and heterocyclic scaffold construction. Our product is rigorously tested for quality, with ??95% purity (HPLC), and is supplied as a white to off-white crystalline powder. Ideal for researchers in medicinal chemistry, agrochemical development, and material science, this compound is packaged under inert conditions to ensure stability and longevity. Available in quantities ranging from milligrams to kilograms, with custom synthesis options upon request.

Application

6-Bromopyridine-2-carboxylic acid serves as a key intermediate in the synthesis of pharmaceuticals, ligands for catalysis, and functionalized pyridine derivatives. It is widely used in Suzuki-Miyaura and Buchwald-Hartwig coupling reactions to construct complex heterocycles. Researchers employ this compound in the development of enzyme inhibitors, receptor modulators, and metal-organic frameworks (MOFs). Its bromine substituent facilitates further functionalization, while the carboxylic acid group allows for conjugation or salt formation.

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