Description

6-Bromopyridin-3-amine (CAS: 13534-97-9) is a high-purity brominated pyridine derivative with the molecular formula C₅H₅BrN₂. This versatile organic compound is widely utilized in pharmaceutical synthesis, agrochemical research, and material science due to its reactive amine and bromine functional groups. Our product is rigorously tested to ensure ≥97% purity (HPLC/GC) and is supplied as a fine crystalline powder with excellent solubility in common organic solvents such as DMSO, ethanol, and dichloromethane. Ideal for Suzuki couplings, Buchwald-Hartwig aminations, and other palladium-catalyzed cross-coupling reactions. Packaged under inert gas in amber glass vials to ensure stability and longevity. SDS and analytical certificates available upon request.

Properties

• CAS Number: 13534-97-9
• Complexity: 76.8
• IUPAC Name: 6-bromopyridin-3-amine
• InChI: InChI=1S/C5H5BrN2/c6-5-2-1-4(7)3-8-5/h1-3H,7H2
• InChI Key: XTHKRYHULUJQHN-UHFFFAOYSA-N
• Exact Mass: 171.96361
• Molecular Formula: C5H5BrN2
• Molecular Weight: 173.01
• SMILES: C1=CC(=NC=C1N)Br
• Topological: 38.9
• Monoisotopic Mass: 171.96361
• Synonyms: 6-bromopyridin-3-amine, 5-Amino-2-bromopyridine, 3-pyridinamine, 6-bromo-, 628-541-3, inchi=1/c5h5brn2/c6-5-2-1-4(7)3-8-5/h1-3h,7h, 13534-97-9, 3-Amino-6-bromopyridine, 2-bromo-5-aminopyridine, 6-bromo-3-pyridinamine, MFCD01646116, 6-bromo-3-pyridylamine, 2-Bromo-5-pyridinamine, 6-bromo-pyridin-3-ylamine, 6-bromopyrid-3-ylamine, 3-amino 6-bromopyridine, 6-bromo-3-aminopyridine, 6-bromopyridine-3-amine, 6-bromopyridin-3-ylamine, 6-Bromo-3-pyridinylamine, 5-amino-2-bromo-pyridine, 6-bromanylpyridin-3-amine, Pyridine, 3-amino-6-bromo-, SCHEMBL106441, 2BU6KLB687, SCHEMBL3701184, 3-Amino-6-bromopyridine, 97%, DTXSID20349069, BDBM105195, BCP22076, BBL100479, RB1035, SBB005540, STL554273, AKOS000275941, AC-2722, CS-W017565, HY-W016849, PB17224, PS-5433, SY002680, DB-006336, A1890, ST51040162, EN300-53250, A806922, AC-907/34116006, Q27454751, 6-Bromopyridin-3-amine;5-Amino-2-bromopyridine;2-Bromo-5-aminopyridine, 4JN

6-Bromopyridin-3-amine serves as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs) and bioactive molecules. It is particularly valuable in constructing pyridine-based scaffolds for kinase inhibitors and receptor modulators. The compound’s bromine moiety enables efficient functionalization via cross-coupling reactions, while the amine group facilitates further derivatization. Researchers also employ it in ligand design for catalysis and as a building block in OLED material development. Proper handling under nitrogen atmosphere is recommended due to its sensitivity to oxidation.

Safety and Hazards

GHS Hazard Statements

• H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H335 (97.9%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Skin Irrit. 2 (100%)
• Eye Irrit. 2 (100%)
• STOT SE 3 (97.9%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.