Get FREE SHIPPING when you spend $99 or more | ATOMFAIR

Awaiting product image

Atomfair 6-Bromo-5-methylpyrazin-2-amine C5H6BrN3 CAS 74290-68-9

6-Bromo-5-methylpyrazin-2-amine (CAS No. 74290-68-9) is a high-purity heterocyclic organic compound with the molecular formula C5H6BrN3. This brominated pyrazine derivative is a valuable building block in pharmaceutical and agrochemical research, offering a reactive bromine substituent for cross-coupling reactions and an amino group for further functionalization. The compound is characterized by its white to off-white crystalline appearance and is supplied with ≥95% purity (HPLC). It is stable under recommended storage conditions (2-8°C, inert atmosphere) and is compatible with common organic solvents, including DMSO, methanol, and dichloromethane. Ideal for medicinal chemistry, this intermediate is particularly useful in the synthesis of kinase inhibitors and…

Category:

Description

6-Bromo-5-methylpyrazin-2-amine (CAS No. 74290-68-9) is a high-purity heterocyclic organic compound with the molecular formula C5H6BrN3. This brominated pyrazine derivative is a valuable building block in pharmaceutical and agrochemical research, offering a reactive bromine substituent for cross-coupling reactions and an amino group for further functionalization. The compound is characterized by its white to off-white crystalline appearance and is supplied with ≥95% purity (HPLC). It is stable under recommended storage conditions (2-8°C, inert atmosphere) and is compatible with common organic solvents, including DMSO, methanol, and dichloromethane. Ideal for medicinal chemistry, this intermediate is particularly useful in the synthesis of kinase inhibitors and other bioactive molecules.

Properties

  • CAS Number: 74290-68-9
  • Complexity: 98.2
  • IUPAC Name: 6-bromo-5-methyl-pyrazin-2-amine
  • InChI: InChI=1S/C5H6BrN3/c1-3-5(6)9-4(7)2-8-3/h2H,1H3,(H2,7,9)
  • InChI Key: LRZBSKCGVMDZHW-UHFFFAOYSA-N
  • Exact Mass: 186.97451
  • Molecular Formula: C5H6BrN3
  • Molecular Weight: 188.03
  • SMILES: CC1=NC=C(N=C1Br)N
  • Topological: 51.8
  • Monoisotopic Mass: 186.97451
  • Synonyms: 6-bromo-5-methylpyrazin-2-amine, 74290-68-9, 2-amino-6-bromo-5-methylpyrazine, MFCD17011819, SCHEMBL15542181, DTXSID70618015, LRZBSKCGVMDZHW-UHFFFAOYSA-N, AKOS015842574, CS-W019079, DS-3869, SY104467, DB-074808, Y10498

Application

6-Bromo-5-methylpyrazin-2-amine serves as a key intermediate in the synthesis of pharmacologically active compounds, particularly in the development of kinase inhibitors for cancer research. Its reactive bromine atom enables participation in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille), while the amino group allows for amide formation or reductive amination. Researchers utilize this compound in fragment-based drug discovery and as a scaffold for building diverse heterocyclic libraries. The methyl substituent enhances metabolic stability in resulting drug candidates, making it valuable for medicinal chemistry optimization programs.

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.

Disclaimer

Intended Use & Restrictions

This product is sold exclusively for laboratory research, analytical testing, or non-commercial purposes.

  • Strictly prohibited: Resale, repackaging, or formulation into commercial products.
  • Not approved for human/animal use, diagnostics, or manufacturing (including pharmaceuticals, agrochemicals, or consumer goods).

Patent & Regulatory Compliance

Certain molecules may be protected by active patents or regulatory restrictions.

  • Buyers must independently verify patent status (e.g., via USPTO/EPO/CNIPA) and comply with local laws.
  • Atomfair LLC does not provide legal assurances regarding patent non-infringement or jurisdictional compliance.

Liability Release

By purchasing, the buyer agrees to:

  • Use this product only as permitted by law.
  • Indemnify Atomfair LLC against all claims arising from misuse, patent infringement, or regulatory violations.

Reviews

There are no reviews yet.

Only logged in customers who have purchased this product may leave a review.

Related products