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Atomfair 5-fluoro-2,3-dihydro-1H-isoindole hydrochloride C8H9ClFN CAS 685565-15-5

5-Fluoro-2,3-dihydro-1H-isoindole hydrochloride (CAS No. 685565-15-5) is a high-purity organic compound with the molecular formula C8H9ClFN. This hydrochloride salt derivative of 5-fluoro-2,3-dihydro-1H-isoindole is a valuable building block in pharmaceutical and agrochemical research. The compound features a fluoro-substituted isoindoline core, offering unique reactivity for heterocyclic synthesis. With a molecular weight of 173.62 g/mol, it is supplied as a white to off-white crystalline powder, typically >95% pure by HPLC. This product is rigorously tested for identity (NMR, MS), purity, and stability, making it ideal for medicinal chemistry applications, including the development of novel bioactive molecules. Store under inert conditions at 2-8°C for optimal…

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Description

5-Fluoro-2,3-dihydro-1H-isoindole hydrochloride (CAS No. 685565-15-5) is a high-purity organic compound with the molecular formula C8H9ClFN. This hydrochloride salt derivative of 5-fluoro-2,3-dihydro-1H-isoindole is a valuable building block in pharmaceutical and agrochemical research. The compound features a fluoro-substituted isoindoline core, offering unique reactivity for heterocyclic synthesis. With a molecular weight of 173.62 g/mol, it is supplied as a white to off-white crystalline powder, typically >95% pure by HPLC. This product is rigorously tested for identity (NMR, MS), purity, and stability, making it ideal for medicinal chemistry applications, including the development of novel bioactive molecules. Store under inert conditions at 2-8°C for optimal shelf life.

Properties

  • CAS Number: 685565-15-5
  • Complexity: 126
  • IUPAC Name: 5-fluoroisoindoline;hydrochloride
  • InChI: InChI=1S/C8H8FN.ClH/c9-8-2-1-6-4-10-5-7(6)3-8;/h1-3,10H,4-5H2;1H
  • InChI Key: NVFMCKBKBMZDOK-UHFFFAOYSA-N
  • Exact Mass: 173.0407551
  • Molecular Formula: C8H9ClFN
  • Molecular Weight: 173.61
  • SMILES: C1C2=C(CN1)C=C(C=C2)F.Cl
  • Topological: 12
  • Monoisotopic Mass: 173.0407551
  • Synonyms: 5-Fluoro-2,3-dihydro-1H-isoindole hydrochloride, 846-038-9, 5-fluoroisoindoline hydrochloride, 685565-15-5, MFCD09832541, 5-fluoro-2,3-dihydro-1H-isoindole;hydrochloride, 5-Fluoro-2,3-dihydro-1h-isoindole, HCl, 5-Fluoro isoindoline hydrochloride, 1H-Isoindole, 5-fluoro-2,3-dihydro-, hydrochloride, 5-fluoroisoindolinehydrochloride, 5-fluoroisoindoline hydrocloride, SCHEMBL1266812, 5-fluoroisoindoline;hydrochloride, DTXSID40591962, NVFMCKBKBMZDOK-UHFFFAOYSA-N, 5-fluoroisoindoline hydrogen chloride, AKOS015902115, AC-7910, CS-W005402, SB64024, SY097472, TS-02392, EN300-98119, 5-FLUORO-2,3-DIHYDRO-1H-ISOINDOLE HCL, 5-Fluoro-2,3-dihydro-1H-isoindole–hydrogen chloride (1/1)

Application

5-Fluoro-2,3-dihydro-1H-isoindole hydrochloride serves as a key intermediate in the synthesis of pharmacologically active compounds, particularly in central nervous system (CNS) drug discovery. The fluorinated isoindoline scaffold is valuable for creating dopamine receptor modulators and serotonin reuptake inhibitors. Researchers utilize this building block to develop novel heterocyclic compounds with potential antidepressant or antipsychotic activity. Its reactivity allows for further functionalization at multiple positions, enabling structure-activity relationship studies.

Safety and Hazards

GHS Hazard Statements

  • H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
  • H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
  • H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
  • H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

  • P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

  • Acute Tox. 4 (100%)
  • Skin Irrit. 2 (100%)
  • Eye Irrit. 2A (100%)
  • STOT SE 3 (100%)

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.

Disclaimer

Intended Use & Restrictions

This product is sold exclusively for laboratory research, analytical testing, or non-commercial purposes.

  • Strictly prohibited: Resale, repackaging, or formulation into commercial products.
  • Not approved for human/animal use, diagnostics, or manufacturing (including pharmaceuticals, agrochemicals, or consumer goods).

Patent & Regulatory Compliance

Certain molecules may be protected by active patents or regulatory restrictions.

  • Buyers must independently verify patent status (e.g., via USPTO/EPO/CNIPA) and comply with local laws.
  • Atomfair LLC does not provide legal assurances regarding patent non-infringement or jurisdictional compliance.

Liability Release

By purchasing, the buyer agrees to:

  • Use this product only as permitted by law.
  • Indemnify Atomfair LLC against all claims arising from misuse, patent infringement, or regulatory violations.

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