Description

5-Fluoro-1,3-thiazol-2-amine hydrochloride (CAS No. 745053-64-9) is a high-purity organic compound with the molecular formula C₃H₄ClFN₂S. This specialized chemical is widely utilized in pharmaceutical research and agrochemical development due to its unique thiazole core structure, which is functionalized with a fluorine atom and an amine group. The hydrochloride salt form enhances its solubility and stability, making it ideal for synthetic applications. With a molecular weight of 154.59 g/mol, this compound is supplied as a white to off-white crystalline powder, ensuring consistent performance in reactions. Its purity is rigorously verified by advanced analytical techniques including HPLC, NMR, and mass spectrometry. Suitable for use in medicinal chemistry, drug discovery, and material science, this product is packaged under inert conditions to maintain its integrity.

Properties

• CAS Number: 745053-64-9
• Complexity: 70
• IUPAC Name: 5-fluorothiazol-2-amine;hydrochloride
• InChI: InChI=1S/C3H3FN2S.ClH/c4-2-1-6-3(5)7-2;/h1H,(H2,5,6);1H
• InChI Key: HUXNGTYNEWXYDM-UHFFFAOYSA-N
• Exact Mass: 153.9767752
• Molecular Formula: C3H4ClFN2S
• Molecular Weight: 154.59
• SMILES: C1=C(SC(=N1)N)F.Cl
• Topological: 67.2
• Monoisotopic Mass: 153.9767752
• Synonyms: 5-fluoro-1,3-thiazol-2-amine Hydrochloride, 829-842-4, 5-fluorothiazol-2-amine hydrochloride, 745053-64-9, 2-Amino-5-fluorothiazole HCl, 2-amino-5-fluorothiazole hydrochloride, 5-fluoro-1,3-thiazol-2-amine;hydrochloride, MFCD09056854, 5-Fluoro-thiazol-2-ylamine hydrochloride, 5-fluorothiazol-2-amine HCl, C3H4ClFN2S, 2-Thiazolamine, 5-fluoro-, monohydrochloride, SCHEMBL184746, DTXSID70474496, HUXNGTYNEWXYDM-UHFFFAOYSA-N, 5-Fluoro-2-thiazolamine hydrochloride, AKOS005258236, 5-fluorothiazol-2-ylamine hydrochloride, DS-12794, SY007487, DB-012268, A9542, CS-0050490, 2-Amino-5-fluorothiazole hydrochloride, 95%, EN300-175962, Z1198184822, 5-fluorothiazol-2-amine hydrochloride;2-AMINO-5-FLUOROTHIAZOLE HCL

5-Fluoro-1,3-thiazol-2-amine hydrochloride serves as a key intermediate in the synthesis of biologically active molecules, particularly in the development of novel pharmaceuticals targeting infectious diseases and metabolic disorders. Its fluorinated thiazole scaffold is valuable for designing enzyme inhibitors and receptor modulators. Researchers also employ this compound in the preparation of agrochemicals due to its potential pesticidal and herbicidal properties. Additionally, it finds use in material science for creating functionalized polymers and coatings.

Safety and Hazards

GHS Hazard Statements

• H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
• H312 (100%): Harmful in contact with skin [Warning Acute toxicity, dermal]
• H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H332 (100%): Harmful if inhaled [Warning Acute toxicity, inhalation]
• H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Acute Tox. 4 (100%)
• Acute Tox. 4 (100%)
• Skin Irrit. 2 (100%)
• Eye Irrit. 2A (100%)
• Acute Tox. 4 (100%)
• STOT SE 3 (100%)

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.