Atomfair 5-fluoro-1,3-dihydro-2H-indol-2-one 5-Fluorooxindole C8H6FNO CAS 56341-41-4

Description

5-Fluoro-1,3-dihydro-2H-indol-2-one (CAS: 56341-41-4) is a high-purity fluorinated oxindole derivative with the molecular formula C₈H₆FNO. This heterocyclic compound is a versatile intermediate in organic synthesis and pharmaceutical research, particularly in the development of bioactive molecules and drug candidates. Its unique structure, featuring a fluorine substituent at the 5-position of the indole ring, enhances its utility in medicinal chemistry for modulating pharmacokinetic properties and binding affinity. Available in ≥97% purity, this product is ideal for researchers requiring precise and reliable building blocks for complex molecular architectures. Packaged under inert conditions to ensure stability, it is suitable for use in high-throughput screening, combinatorial chemistry, and target-specific drug discovery programs.

Properties

• CAS Number: 56341-41-4
• Complexity: 183
• IUPAC Name: 5-fluoroindolin-2-one
• InChI: InChI=1S/C8H6FNO/c9-6-1-2-7-5(3-6)4-8(11)10-7/h1-3H,4H2,(H,10,11)
• InChI Key: DDIIYGHHUMKDGI-UHFFFAOYSA-N
• Exact Mass: 151.043341977
• Molecular Formula: C8H6FNO
• Molecular Weight: 151.14
• SMILES: C1C2=C(C=CC(=C2)F)NC1=O
• Topological: 29.1
• Monoisotopic Mass: 151.043341977
• Synonyms: 5-fluoro-1,3-dihydroindol-2-one, 5-fluoro-1,3-dihydro-2H-indol-2-one, 638-803-9, 5-Fluorooxindole, 56341-41-4, 5-Fluoro-2-oxindole, 5-fluoroindolin-2-one, 2H-Indol-2-one, 5-fluoro-1,3-dihydro-, 5-fluoro-2,3-dihydro-1H-indol-2-one, 5-Fluoro-2-oxoindoline, MFCD02179598, 5-Fluoro-2,3-dihydro-2-oxoindole, 4EW64J5JHC, 5-Fluoranyl-1,3-dihydroindol-2-one, FLUOROOXINDOLE, 5-Fluorooxindole (5-Fluoro-1,3-dihydro-2H-indol-2-one), Oxindole derivative, 5-Fluoro-2-indolinone, 5-Fluoro-1,3-dihydro-indol-2-one, 5-fluoroindolinone, 5-fluoro-oxindole, UNII-4EW64J5JHC, SCHEMBL152963, 5-Fluoro-2-oxindole, 97%, SCHEMBL7572657, DTXSID40395649, WLZ3258, DDIIYGHHUMKDGI-UHFFFAOYSA-N, BCP27225, 5-fluoro-1, 3-dihydroindol-2-one, 5-fluoro-1,3-dihydro-indo1-2-one, 5-fluoro-1,3-dihydro-indole-2-one, BBL012822, SBB018719, STK787818, AKOS005255291, AB11374, AC-2684, BCP9000184, BH-0437, CS-W002914, FF01460, HY-W002914, 5-fluoro-1.3-dihydro-2H-indol-2-one, BP-21383, SY002547, DB-007049, DB-219503, ST4145632, F0699, EN300-106959

5-Fluoro-1,3-dihydro-2H-indol-2-one is widely used as a key intermediate in the synthesis of pharmaceuticals, particularly for central nervous system (CNS) agents and kinase inhibitors. Its fluorinated oxindole scaffold is valuable for designing protease inhibitors and anticancer compounds due to its ability to enhance metabolic stability. Researchers also employ it in fragment-based drug discovery (FBDD) and as a precursor for fluorescent probes in biochemical assays.

Safety and Hazards

GHS Hazard Statements

• H301 (78.4%): Toxic if swallowed [Danger Acute toxicity, oral]
• H315 (18.9%): Causes skin irritation [Warning Skin corrosion/irritation]
• H319 (18.9%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• H335 (18.9%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statements

• P261, P264, P264+P265, P270, P271, P280, P301+P316, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

Hazard Classes and Categories

• Acute Tox. 3 (78.4%)
• Skin Irrit. 2 (18.9%)
• Eye Irrit. 2A (18.9%)
• STOT SE 3 (18.9%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.