Description
5-Ethyluracil (CAS No. 4212-49-1) is a high-purity pyrimidine derivative with the molecular formula C6H8N2O2 and the IUPAC name 5-ethyl-1H-pyrimidine-2,4-dione. This compound is a modified uracil analog, featuring an ethyl substitution at the 5-position, which enhances its utility in nucleoside chemistry and biochemical research. Our 5-Ethyluracil is rigorously tested for purity and stability, making it ideal for pharmaceutical research, nucleic acid studies, and as a building block in organic synthesis. Available in various quantities, this product is packaged under controlled conditions to ensure optimal shelf life and performance.
Properties
- CAS Number: 4212-49-1
- Complexity: 208
- IUPAC Name: 5-ethyl-1H-pyrimidine-2,4-dione
- InChI: InChI=1S/C6H8N2O2/c1-2-4-3-7-6(10)8-5(4)9/h3H,2H2,1H3,(H2,7,8,9,10)
- InChI Key: RHIULBJJKFDJPR-UHFFFAOYSA-N
- Exact Mass: 140.058577502
- Molecular Formula: C6H8N2O2
- Molecular Weight: 140.14
- SMILES: CCC1=CNC(=O)NC1=O
- Topological: 58.2
- Monoisotopic Mass: 140.058577502
- Synonyms: 5-Ethyluracil, 4212-49-1, 2,4(1H,3H)-Pyrimidinedione, 5-ethyl-, DTXSID60194959, 5-ethyl-2,4(1H,3H)-pyrimidinedione, DTXCID50117450, 443-780-1, 622-736-7, 5-Ethyl uracil, 5-ethyl-1H-pyrimidine-2,4-dione, 2,4-Dihydroxy-5-ethylpyrimidine, MFCD00079187, 5-ethylpyrimidine-2,4(1h,3h)-dione, 5-ethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione, Uracil, 5-ethyl-, 5-ethyl-1,3-dihydropyrimidine-2,4-dione, SCHEMBL161148, SCHEMBL3138242, 5-Ethyl-2,4-pyrimidinediol #, SCHEMBL14048734, CS-B1504, AKOS005206784, AC-1385, FE08009, GS-3069, SB57227, SY002972, pyrimidine-2,4(1H,3H)-dione, 5-ethyl-, 2,4-Dihydroxy-5-ethylpyrimidine;Homothymine, E0807, ST50823668, 2,4-Dihydroxy-5-ethylpyrimidine, Homothymine, EN300-95986, H10158, 1,2,3,4-Tetrahydropyrimidine, 5-ethyl-2,4-dioxo-
Application
5-Ethyluracil is widely used as a precursor in the synthesis of modified nucleosides and nucleotides, particularly in antiviral and anticancer drug development. It serves as a key intermediate in the study of nucleic acid metabolism and enzyme inhibition mechanisms. Researchers also utilize this compound to investigate the effects of alkyl substitutions on uracil’s hydrogen-bonding properties and base-pairing behavior in DNA/RNA analogs.
Safety and Hazards
GHS Hazard Statements
- H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
- H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
- H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
Precautionary Statements
- P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501
Hazard Classes and Categories
- Skin Irrit. 2 (100%)
- Eye Irrit. 2 (100%)
- STOT SE 3 (100%)
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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.


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