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Atomfair 5-Chloro-2,3-difluoropyridine C5H2ClF2N CAS 89402-43-7

5-Chloro-2,3-difluoropyridine (CAS No. 89402-43-7) is a high-purity fluorinated pyridine derivative with the molecular formula C5H2ClF2N . This heterocyclic compound is characterized by its chloro and difluoro substitutions at the 5, 2, and 3 positions, respectively, making it a versatile intermediate in pharmaceutical and agrochemical synthesis. Its precise molecular structure ensures excellent reactivity in cross-coupling reactions, nucleophilic substitutions, and other functionalization processes. Packaged under inert conditions to maintain stability, this compound is ideal for research and industrial applications requiring stringent quality standards. Available in quantities ranging from grams to kilograms, it is supplied with comprehensive analytical data (including GC/MS, NMR, and…

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Description

5-Chloro-2,3-difluoropyridine (CAS No. 89402-43-7) is a high-purity fluorinated pyridine derivative with the molecular formula C5H2ClF2N. This heterocyclic compound is characterized by its chloro and difluoro substitutions at the 5, 2, and 3 positions, respectively, making it a versatile intermediate in pharmaceutical and agrochemical synthesis. Its precise molecular structure ensures excellent reactivity in cross-coupling reactions, nucleophilic substitutions, and other functionalization processes. Packaged under inert conditions to maintain stability, this compound is ideal for research and industrial applications requiring stringent quality standards. Available in quantities ranging from grams to kilograms, it is supplied with comprehensive analytical data (including GC/MS, NMR, and HPLC) to guarantee purity and consistency.

Properties

  • CAS Number: 89402-43-7
  • Complexity: 101
  • IUPAC Name: 5-chloro-2,3-difluoro-pyridine
  • InChI: InChI=1S/C5H2ClF2N/c6-3-1-4(7)5(8)9-2-3/h1-2H
  • InChI Key: PERMDYZFNQIKBL-UHFFFAOYSA-N
  • Exact Mass: 148.9843831
  • Molecular Formula: C5H2ClF2N
  • Molecular Weight: 149.52
  • SMILES: C1=C(C=NC(=C1F)F)Cl
  • Topological: 12.9
  • Monoisotopic Mass: 148.9843831
  • Synonyms: 5-Chloro-2,3-difluoropyridine, 89402-43-7, 2,3-Difluoro-5-chloropyridine, NTR2GM7GHF, EC 410-090-7, DTXSID001008801, Pyridine, 5-chloro-2,3-difluoro-, DTXCID001435632, 410-090-7, 618-273-5, MFCD04039314, 2,3-DIFLUORO-5-CHLORO PYRIDINE, 589402-43-7, 2,3-Difluoro-5-chloropyridine; 3-Chloro-5,6-difluoropyridine;, 3-chloro-5,6-difluoropyridine, 5-chloro-2,3-difluoro-pyridine, UNII-NTR2GM7GHF, SCHEMBL47044, SBB086666, AKOS005064057, 2,3-Difluoro-5-chloropyridine, 95%, AC-8181, CS-W003144, FG-0488, AC-23446, DB-027547, DB-292156, C2113, NS00005305, ST50824183, EN300-98067, Z1255442949

Application

5-Chloro-2,3-difluoropyridine serves as a key building block in the synthesis of advanced pharmaceutical compounds, particularly in the development of kinase inhibitors and antimicrobial agents. Its fluorinated pyridine core is instrumental in agrochemical research for creating novel herbicides and pesticides with enhanced activity. The compound’s reactivity also makes it valuable in material science for designing fluorinated liquid crystals or electronic materials.

Safety and Hazards

GHS Hazard Statements

  • H226: Flammable liquid and vapor [Warning Flammable liquids]
  • H302: Harmful if swallowed [Warning Acute toxicity, oral]
  • H412: Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]

Precautionary Statements

  • P210, P233, P240, P241, P242, P243, P264, P270, P273, P280, P301+P317, P303+P361+P353, P330, P370+P378, P403+P235, and P501

Hazard Classes and Categories

  • Flam. Liq. 3 (100%)
  • Acute Tox. 4 (98.8%)
  • Aquatic Chronic 3 (98.8%)

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Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.

Disclaimer

Intended Use & Restrictions

This product is sold exclusively for laboratory research, analytical testing, or non-commercial purposes.

  • Strictly prohibited: Resale, repackaging, or formulation into commercial products.
  • Not approved for human/animal use, diagnostics, or manufacturing (including pharmaceuticals, agrochemicals, or consumer goods).

Patent & Regulatory Compliance

Certain molecules may be protected by active patents or regulatory restrictions.

  • Buyers must independently verify patent status (e.g., via USPTO/EPO/CNIPA) and comply with local laws.
  • Atomfair LLC does not provide legal assurances regarding patent non-infringement or jurisdictional compliance.

Liability Release

By purchasing, the buyer agrees to:

  • Use this product only as permitted by law.
  • Indemnify Atomfair LLC against all claims arising from misuse, patent infringement, or regulatory violations.

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