Get FREE SHIPPING when you spend $99 or more | ATOMFAIR

Awaiting product image

Atomfair 5-Chloro-2-fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline C12H16BClFNO2 CAS 1269232-96-3

5-Chloro-2-fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline (CAS No. 1269232-96-3) is a high-purity boronic ester derivative with the molecular formula C12H16BClFNO2. This compound is a valuable intermediate in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds in complex molecular architectures. Its stable dioxaborolane ring and reactive aniline group make it ideal for pharmaceutical research, agrochemical development, and materials science applications. The product is supplied as a crystalline solid with >95% purity (HPLC), ensuring consistency for sensitive synthetic workflows. Store under inert conditions at 2-8°C to maintain stability.

Category:

Description

5-Chloro-2-fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline (CAS No. 1269232-96-3) is a high-purity boronic ester derivative with the molecular formula C12H16BClFNO2. This compound is a valuable intermediate in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds in complex molecular architectures. Its stable dioxaborolane ring and reactive aniline group make it ideal for pharmaceutical research, agrochemical development, and materials science applications. The product is supplied as a crystalline solid with >95% purity (HPLC), ensuring consistency for sensitive synthetic workflows. Store under inert conditions at 2-8°C to maintain stability.

Properties

  • CAS Number: 1269232-96-3
  • Complexity: 313
  • IUPAC Name: 5-chloro-2-fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline
  • InChI: InChI=1S/C12H16BClFNO2/c1-11(2)12(3,4)18-13(17-11)8-5-7(14)6-9(16)10(8)15/h5-6H,16H2,1-4H3
  • InChI Key: WFFDTMNHOINATE-UHFFFAOYSA-N
  • Exact Mass: 271.0946648
  • Molecular Formula: C12H16BClFNO2
  • Molecular Weight: 271.52
  • SMILES: B1(OC(C(O1)(C)C)(C)C)C2=CC(=CC(=C2F)N)Cl
  • Topological: 44.5
  • Monoisotopic Mass: 271.0946648
  • Synonyms: 1269232-96-3, 5-chloro-2-fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline, Benzenamine, 5-chloro-2-fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, WFFDTMNHOINATE-UHFFFAOYSA-N, MFCD22189454, SCHEMBL1494585, DTXSID70725899, ZB1265, AS-78208, DB-100272, CS-0196654, 5-Chloro-2-fluoroaniline-3-boronic acid pinacol ester, 5-chloro-2-fluoro-3-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)benzenaMine

Application

This compound is widely used as a key building block in palladium-catalyzed cross-coupling reactions for synthesizing biaryl structures found in drug candidates. It serves as a precursor for fluorinated pharmaceutical intermediates and functional materials. Researchers utilize it in medicinal chemistry to introduce chloro-fluoro-aniline motifs into target molecules. The boronic ester moiety provides excellent stability while maintaining reactivity for diverse transformations.

If you are interested or have any questions, please contact us at support@atomfair.com

Disclaimer: Sold exclusively for laboratory research. Prohibited for commercial use, diagnostics, or human/animal applications. Buyers assume all compliance liability.

Disclaimer

Intended Use & Restrictions

This product is sold exclusively for laboratory research, analytical testing, or non-commercial purposes.

  • Strictly prohibited: Resale, repackaging, or formulation into commercial products.
  • Not approved for human/animal use, diagnostics, or manufacturing (including pharmaceuticals, agrochemicals, or consumer goods).

Patent & Regulatory Compliance

Certain molecules may be protected by active patents or regulatory restrictions.

  • Buyers must independently verify patent status (e.g., via USPTO/EPO/CNIPA) and comply with local laws.
  • Atomfair LLC does not provide legal assurances regarding patent non-infringement or jurisdictional compliance.

Liability Release

By purchasing, the buyer agrees to:

  • Use this product only as permitted by law.
  • Indemnify Atomfair LLC against all claims arising from misuse, patent infringement, or regulatory violations.

Reviews

There are no reviews yet.

Only logged in customers who have purchased this product may leave a review.

Related products