Description

Description

5-Bromo-6-methylpyridine-2-carbonitrile (CAS No. 1173897-86-3) is a high-purity heterocyclic organic compound with the molecular formula C₇H₅BrN₂. This brominated pyridine derivative features a nitrile functional group at the 2-position and a methyl group at the 6-position, making it a versatile intermediate for pharmaceutical and agrochemical synthesis. Its precise molecular structure (IUPAC name: 5-bromo-6-methylpyridine-2-carbonitrile) ensures consistent reactivity in cross-coupling reactions, nucleophilic substitutions, and other transformations. Supplied as a crystalline solid with ??95% purity (HPLC), it is rigorously tested for trace metals, residual solvents, and moisture content. Ideal for medicinal chemistry, this compound is packaged under inert gas in amber glass vials to ensure stability and longevity. Available in research (mg to g) and bulk (kg) quantities with optional custom purity and packaging.

Application

5-Bromo-6-methylpyridine-2-carbonitrile serves as a key building block in the synthesis of bioactive molecules, particularly in the development of kinase inhibitors and antiviral agents. Its bromine and nitrile groups enable efficient Suzuki-Miyaura and cyanation reactions for derivatization. Researchers utilize this compound in fragment-based drug discovery (FBDD) due to its balanced lipophilicity and hydrogen-bonding capacity. It is also employed in material science for constructing nitrogen-rich ligands in coordination chemistry.

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